Eclampsia tied to increased relative risk of seizure disorder

November 10, 2017

(HealthDay)—The relative risk of a seizure disorder after eclampsia is higher than that of women unaffected by eclampsia but remains extremely low, according to a study published online Nov. 7 in Obstetrics & Gynecology.

Kara A. Nerenberg, M.D., from the University of Calgary in Canada, and colleagues retrospectively evaluated data from 1,565,733 births from April 1, 2002, to March 31, 2014, to evaluate the incidence rate and relative risk of a seizure disorder after eclampsia.

The researchers found that 0.1 percent of pregnancies were affected by eclampsia, 1.1 percent by pre-eclampsia, and 3.9 percent by gestational hypertension. After a pregnancy with eclampsia, a future seizure disorder was significantly more likely (4.58/10,000 person-years) compared with a pregnancy without a of pregnancy (0.72/10,000 person-years; crude hazard ratio [HR], 6.09). This finding remained with minimal attenuation after multivariable adjustment for confounders (HR, 5.42). After pre-eclampsia, the risk of seizure disorder was doubled (adjusted HR, 1.96; 95 percent confidence interval, 1.21 to 3.17), but this was not the case after gestational hypertension (adjusted HR, 1.01; 95 percent confidence interval, 0.71 to 1.43).

"Women with eclampsia should be reassured that, although the relative risk of a is higher than unaffected women, the absolute risk is extremely low (approximately one seizure/2,200 person-years)," write the authors.

Explore further: Early onset of pregnancy complication may raise heart risks

More information: Abstract/Full Text (subscription or payment may be required)

Related Stories

Early onset of pregnancy complication may raise heart risks

September 15, 2017
(HealthDay)—Women who develop pre-eclampsia earlier in pregnancy may be at increased risk for heart problems soon after giving birth, a new study finds.

Mothers with pre-eclampsia may encounter challenges later in life

August 25, 2017
A new study has found that a condition that threatens the lives of some pregnant women and the fetus may continue to put the mother at risk later in life.

Maternal C-type natriuretic peptide tied to pre-eclampsia

April 10, 2015
(HealthDay)—Levels of maternal plasma amino terminal propeptide of C-type natriuretic peptide (NTproCNP) may be useful in defining phenotypes associated with pre-eclampsia in late pregnancy, according to a study published ...

Hypertensive disorders during pregnancy increase risk for high blood pressure after delivery

January 28, 2016
Women who are diagnosed with hypertensive disorders while pregnant are more than twice as likely to develop high blood pressure in the first year after delivery as women who did not have any pregnancy-related hypertension, ...

Serum biomarkers can predict women at risk of pre-eclampsia

July 22, 2015
Levels of biomarkers in the blood of pregnant women can be used to predict which women are at risk of pre-eclampsia, finds a study published today (22 July) in BJOG: An International Journal of Obstetrics and Gynaecology ...

Finnish mothers discovered to have gene variants that protect them from pre-eclampsia

July 3, 2017
Researchers at the University of Helsinki, in cooperation with two research groups in the United States, have discovered that some Finnish mothers carry rare gene variants that protect them from pre-eclampsia, also known ...

Recommended for you

Undiagnosed STIs can increase negative PMS symptoms

September 17, 2018
Women that have undiagnosed sexually transmitted infections may be at greater risk of experiencing negative premenstrual symptoms (PMS), according to new Oxford University research.

High dose folic acid does not prevent pre-eclampsia in high risk women

September 13, 2018
Taking high dose folic acid supplements in later pregnancy (beyond the first trimester) does not prevent pre-eclampsia in women at high risk for this condition, finds a randomised controlled trial published by The BMJ today.

Study finds air purifiers may benefit fetal growth

September 12, 2018
A new study led by SFU health sciences researchers Prabjit Barn and Ryan Allen reveals fetal growth may improve if pregnant women use portable air purifiers inside their homes.

Delayed childbearing is a growing source of multiple births, study shows

September 12, 2018
Starting in the 1980s, the number of multiple births—twins, triplets, quadruplets and quintuplets—steadily increased from about 20 sets per 1,000 live births to almost 35 sets per 1,000 live births in the 2010s.

Transforming pregnancy research with a smartphone app

September 5, 2018
For years, pregnant women have been underrepresented in biomedical research. Current treatments, interventions and guidelines do a poor job of taking into consideration the diverse characteristics of all pregnant women.

For women undergoing IVF, is fresh or frozen embryo transfer best?

August 21, 2018
The world's first baby born via in-vitro fertilization turned 40 years old this summer. Still, after four decades, IVF is a relatively new field with ongoing debate on how to get the best results for families who have placed ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.