Imaging features predict tumor grade

The vast majority of meningiomas—tumors that form from the membranes surrounding the brain and spinal cord—are slow-growing and benign. "Atypical" meningiomas have a more aggressive clinical course, and patients with atypical tumors would potentially benefit from earlier surgery and efforts to achieve complete tumor removal.

Andrew Hale, an MD/PhD candidate at Vanderbilt, Lola Chambless, MD, and colleagues reviewed (MRI) studies for 128 patients who had benign or atypical meningiomas surgically removed.

They found that tumor volume was the most striking single predictor of tumor grade. Additional imaging features associated with increased risk for atypical pathology included the presence of , swelling around the tumor (peritumoral edema) and tumor location.

The findings, reported in the February issue of the Journal of Clinical Neuroscience, demonstrate the contribution of volume to atypical meningioma pathology and may help guide surgical planning and patient counseling.

Explore further

What turns benign central nervous system tumors deadly

More information: Andrew T. Hale et al. Differentiating meningioma grade by imaging features on magnetic resonance imaging, Journal of Clinical Neuroscience (2017). DOI: 10.1016/j.jocn.2017.11.013
Citation: Imaging features predict tumor grade (2018, January 30) retrieved 25 February 2021 from
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Feedback to editors

User comments