Red wine proves good for the heart (again)

February 1, 2018, Louisiana State University
Credit: CC0 Public Domain

Antioxidant compounds found in red wine are advancing the treatment of heart disease—the leading cause of death for both men and women in the U.S.

Heart disease occurs when plaque builds up within artery walls blocking the blood flow through tissues in the body, increasing the risk of a heart attack or stroke. About 630,000 people die each year from , according to the Centers for Disease Control and Prevention.

While there is no singular cure for heart disease, there are numerous forms of treatment including lifestyle changes and surgical procedures. In one procedure called a coronary angioplasty, a surgeon inserts and inflates a tiny balloon inside a blocked or narrow artery to widen it and allow blood to flow through to the heart thereby decreasing the risk of a or stroke. This procedure often includes inserting a permanent small mesh tube to support the blood vessel called a stent.

Commercial stents can release chemotherapy agents that are toxic and can cause the blood vessel to narrow again. LSU Department of Comparative Biomedical Sciences Professor Tammy Dugas is developing a new stent that releases red wine antioxidants slowly over time that promotes healing and prevents blood clotting and inflammation. The two are resveratrol and quercetin.

"By delivering red wine antioxidants during conventional angioplasty, it may be possible to prevent excess tissue from building up and the blood vessel from narrowing again as it heals," Dr. Dugas said.

In addition to the stent, Dugas and colleagues are developing a balloon coated with the same compounds to treat blood flow blockages throughout the body called . This disease which can limit the to kidneys, the stomach, arms or legs affects about 8 to 12 million Americans. However, less than 20 percent are diagnosed by a physician. Drug-coated balloons are a relatively new product, and are being developed to help interventional cardiologists treat arteries that are difficult to target with traditional angioplasty and stent treatments.

Explore further: One type of heart disease requires special testing

Related Stories

One type of heart disease requires special testing

January 3, 2018
Today's technology has made tremendous strides in the diagnosis and treatment of heart disease but until recently it was tricky to diagnose a heart condition called Microvascular Coronary Dysfunction (MCD).

Stents may reduce heart attacks by delivering downstream medication

September 15, 2011
Researchers at Cleveland Clinic have discovered that cardiac patients receiving medicated stents -- a procedure that occurs often when blood vessels are blocked -- have a lower likelihood of suffering heart attacks or developing ...

Anti-clotting drug approved for angioplasty

June 23, 2015
(HealthDay)—Kengreal (cangrelor) has been approved by the U.S. Food and Drug Administration to prevent blood clots from forming during angioplasty.

Heart bypass surgery outperforms new generation stents

March 16, 2015
Despite the advent of a new generation of stents, patients with multiple narrowed arteries in the heart who received coronary artery bypass grafting fared better than those whose arteries were opened with balloon angioplasty ...

New coating may reduce blood clot risk inside stents

September 5, 2013
Coating artery-opening stents with a new compound may someday eliminate a common side effect of the treatment, according to preliminary research in the American Heart Association journal Arteriosclerosis, Thrombosis, and ...

A simple fix to avoid some unnecessary coronary stents

March 20, 2017
Physician researchers at Thomas Jefferson University suspect that some cases of coronary artery spasm go unrecognized and are incorrectly treated with stents. The good news - there could be a simple fix to eliminate these ...

Recommended for you

Non-coding genetic variant could improve key vascular functions

November 15, 2018
Atherosclerotic disease, the slow and silent hardening and narrowing of the arteries, is a leading cause of mortality worldwide. It is responsible for more than 15 million deaths each year, including an estimated 610,000 ...

Study of two tribes sheds light on role of Western-influenced diet in blood pressure

November 14, 2018
A South American tribe living in near-total isolation with no Western dietary influences showed no increase in average blood pressure from age one to age 60, according to a study led by researchers at Johns Hopkins Bloomberg ...

Heart failure patients shouldn't stop meds even if condition improves: study

November 13, 2018
(HealthDay)—There's bad news for heart failure patients with dilated cardiomyopathy who'd like to stop taking their meds.

Bypass beats stents for diabetics with heart trouble: study

November 13, 2018
(HealthDay)—People with both diabetes and multiple clogged heart arteries live longer if they undergo bypass surgery rather than have their blood vessels reopened with stents, according to follow-up results from a landmark ...

Kawasaki disease: One disease, multiple triggers

November 12, 2018
Researchers at University of California San Diego School of Medicine, Scripps Institution of Oceanography, and international collaborators have evidence that Kawasaki Disease (KD) does not have a single cause. By studying ...

New treatment significantly reduces cardiovascular events when combined with statins

November 12, 2018
Statins are the most commonly used treatment for cardiovascular disease. Despite reducing certain risk factors, if triglyceride levels remain high with use of statins, there is still a significant risk for heart attack, stroke ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.