Risk of breast CA may be higher in women with schizophrenia

Risk of breast CA may be higher in women with schizophrenia

(HealthDay)—The incidence of breast cancer in women with schizophrenia may be higher than that of the general female population, according to a review and meta-analysis published online March 7 in JAMA Psychiatry.

Chuanjun Zhuo, M.D., Ph.D., from Tianjin Medical University in China, and Patrick Todd Triplett, M.D., from Johns Hopkins University in Baltimore, conducted a systematic literature review to identify cohort studies reporting the standardized incidence ratio (SIR) for the risk of in women with compared with the .

The researchers included 12 cohorts (760 women) in this meta-analysis. Pooled analysis showed that schizophrenia was associated with a significantly increased risk of breast cancer incidence in women (SIR, 1.31; P < 0.001). However, substantial between-study variance, as suggested by the wide prediction interval (0.81 to 2.10), indicated the possibility that a future study could show different results. Additionally, subgroup analysis showed that the association was not significantly affected by either the sample size of included studies or exclusion of breast cancer cases at baseline.

"The incidence of breast cancer in with schizophrenia is higher than that of the general female population. However, significant heterogeneity exists among the included studies," the authors write. "Women with schizophrenia deserve intensive prevention and treatment of breast cancer."

Explore further

Consumption of processed meat may increase the risk of breast cancer, according to a new study.

More information: Abstract/Full Text (subscription or payment may be required)
Journal information: JAMA Psychiatry

Copyright © 2018 HealthDay. All rights reserved.

Citation: Risk of breast CA may be higher in women with schizophrenia (2018, March 16) retrieved 2 August 2021 from https://medicalxpress.com/news/2018-03-breast-ca-higher-women-schizophrenia.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Feedback to editors

User comments