Choroidal thickness changes in patients with untreated DM

April 23, 2018

(HealthDay)—The choroidal thickness changes in patients with untreated diabetes mellitus over time, according to a study published online April 14 in Clinical & Experimental Ophthalmology.

Hiroaki Endo, from Teine Keijinkai Hospital in Sapporo, Japan, and colleagues examined the choroidal thickness in 268 eyes of 134 patients with diabetes mellitus and 72 healthy controls (92 eyes) to compare the findings based on medical history of systemic diabetes mellitus treatments and stage of diabetic retinopathy (DR).

The researchers observed a strong correlation between masked raters of choroidal thickness measurements, proving high reproducibility. In the untreated diabetes mellitus group, the total and outer choroid thicknesses in mild/moderate non-proliferative DR (mNPDR) were significantly thinner versus normal controls. In severe NPDR, choroidal outer layer thickness in the untreated group was significantly thicker than normal controls. However, in the group treated for mellitus, there were no significant differences regarding choroidal layer thicknesses and all stages of DR.

"The choroidal thickness significantly changed in the untreated group, and the main anatomical changes might result from the outer layer," the authors write.

Explore further: Specific vascular flow void in acute macular neuroretinopathy

More information: Abstract/Full Text (subscription or payment may be required)

Related Stories

Specific vascular flow void in acute macular neuroretinopathy

September 29, 2017
(HealthDay)—Patients with acute macular neuroretinopathy (AMN) have areas of inner choroidal vascular flow void on optical coherence tomography angiography (OCTA), and these may persist for weeks after symptom onset, according ...

Diabetes tied to higher rates of serious infection

January 23, 2018
(HealthDay)—Patients with diabetes, particularly type 1 diabetes mellitus (T1DM), are at increased risk of serious infection, according to a study published online Jan. 12 in Diabetes Care.

Higher AlphaB-crystallin levels linked to diabetic retinopathy

December 21, 2016
(HealthDay)—Vitreous levels of alphaB-crystallin are significantly higher in eyes of patients with proliferative diabetic retinopathy (PDR) compared to the eyes of controls without diabetes, according to a study published ...

Artemisia extract ups insulin sensitivity in GDM

May 3, 2016
(HealthDay)—For women with gestational diabetes mellitus, daily administration of Artemisia extract is associated with improved insulin sensitivity, according to a study published online April 27 in the Journal of Clinical ...

Diet soda associated with higher odds of diabetic retinopathy

January 30, 2018
(HealthDay)—Diet soda consumption may up the odds of diabetic retinopathy (DR), according to a study published online Jan. 23 in Clinical & Experimental Ophthalmology.

Pre-op liraglutide cuts post-op plasma glucose in T2DM

December 19, 2017
(HealthDay)—For patients with type 2 diabetes mellitus undergoing non-cardiac surgery, premedication with liraglutide is associated with reduced median plasma glucose one hour postoperatively, according to a study published ...

Recommended for you

Microglia protect sensory cells needed for vision after retinal detachment

June 18, 2018
A research team at Massachusetts Eye and Ear has shown that microglia, the primary immune cells of the brain and retina, play a protective role in response to retinal detachment. Retinal detachment and subsequent degeneration ...

161 genetic factors for myopia identified

June 15, 2018
The international Consortium for Refractive Error and Myopia (CREAM) recently published the largest-ever genetic study of myopia in Nature Genetics. Researchers from the Gutenberg Health Study at the Medical Center of Johannes ...

Normal eye dominance is not necessary for restoring visual acuity in amblyopia

June 7, 2018
Amblyopia, commonly known as "lazy eye," is a visual disorder common in children. The symptoms often are low acuity in the affected or "lazy" eye and impaired depth perception. Researchers have long believed that the impaired ...

Education linked to higher risk of short-sightedness

June 6, 2018
Spending more years in full time education is associated with a greater risk of developing short-sightedness (myopia), finds a study published by The BMJ today.

First 3D-printed human corneas

May 29, 2018
The first human corneas have been 3-D printed by scientists at Newcastle University, UK.

Satellite imaging techniques may help reduce preventable vision loss

May 11, 2018
By adapting pattern recognition techniques used to assess satellite images, scientists have devised a novel way to diagnose blinding eye diseases, such as age-related macular degeneration.


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.