Vitamin A appears helpful in pediatric retinitis pigmentosa

Vitamin A appears helpful in pediatric retinitis pigmentosa
(HealthDay)—For children with retinitis pigmentosa, vitamin A supplementation is associated with slower loss of cone electroretinogram amplitude, according to a study published online March 29 in JAMA Ophthalmology.

Eliot L. Berson, M.D., from Harvard Medical School in Boston, and colleagues conducted a nonrandomized comparison study involving children with taking or not taking A supplementation (55 and 25, respectively). The main outcome was the mean exponential rates of change of full-field cone electroretinogram to 30-Hz flashes.

The researchers found that in the unadjusted model, the estimated mean rates of change were −0.0713 loge unit/year for the vitamin A cohort and −0.1419 loge unit per year for the control cohort (−6.9 and −13.2 percent per year, respectively). A slower mean rate of decline was confirmed in the vitamin A cohort in the adjusted model (difference, 0.0771 loge-unit per year). There was no difference by cohort in the mean exponential rates of change of visual field area and and the incidences of falling to a visual field diameter of 20 degrees or less or a visual acuity of 20/200 or less in at least one eye.

"A vitamin A palmitate supplement was associated with a slower loss of cone electroretinogram amplitude in children with retinitis pigmentosa," the authors write.


Explore further

Gene mutation linked to retinitis pigmentosa in Southwestern US Hispanic families

More information: Abstract/Full Text
Editorial (subscription or payment may be required)

Copyright © 2018 HealthDay. All rights reserved.

Citation: Vitamin A appears helpful in pediatric retinitis pigmentosa (2018, April 2) retrieved 23 March 2019 from https://medicalxpress.com/news/2018-04-vitamin-pediatric-retinitis-pigmentosa.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
3 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more