No benefit to negative pressure wound therapy after C-section

September 28, 2018

(HealthDay)—For obese women, use of prophylactic negative pressure wound therapy versus standard dressings does not reduce superficial surgical site infections after cesarean section, according to a study published in the August issue of Obstetrics & Gynecology.

Kristina A. Wihbey, M.D., from the Geisel School of Medicine at Dartmouth in Lebanon, N.H., and colleagues conducted a randomized controlled, non-blinded study to compare prophylactic negative pressure with standard surgical dressings placed at the time of primary closure of cesarean delivery in obese women with body mass indexes of 35 kg/m² or higher. The authors intended to recruit 400 women, but after low enrollment of 166 women over 24 months, an interim analysis was conducted for futility, and the study was halted.

The researchers found no difference between the groups in the occurrence of observed superficial (prophylactic negative pressure wound therapy group, 15 percent, versus 10 percent for women receiving the standard dressing; P = 0.35). Women receiving prophylactic negative pressure wound therapy and those receiving the standard dressing had no differences in the occurrence of composite wound complications (31 versus 30 percent; P = 0.87).

"In this randomized controlled trial that did not achieve full anticipated enrollment, we did not observe a decrease in superficial surgical site infections after cesarean delivery in with the use of negative pressure wound therapy," the authors write.

The devices used in the study were provided by an unrestricted grant from KCI Medical.

Explore further: Antibiotics following C-section among obese women reduces risk of surgical infection

More information: Abstract/Full Text

Related Stories

Antibiotics following C-section among obese women reduces risk of surgical infection

September 19, 2017
Among obese women undergoing cesarean delivery, a postoperative 48-hour course of antibiotics significantly decreased the rate of surgical site infection within 30 days after delivery, according to a study published by JAMA.

Prophylactic tranexamic acid doesn't cut postpartum bleeding

August 23, 2018
(HealthDay)—Prophylactic administration of tranexamic acid does not reduce postpartum hemorrhage among women with vaginal delivery receiving prophylactic oxytocin, according to a study published in the Aug. 23 issue of ...

Equal wound complications for staples, suture in obese women

June 9, 2017
(HealthDay)—The rate of surgical site wound complications is similar for obese women undergoing midline vertical incision with skin closure via staples or subcuticular suture, according to a study published in the July ...

Skin microbiota differ for obese, non-obese undergoing c-section

August 28, 2018
(HealthDay)—After cesarean delivery (CD), the incision site harbors a higher bacterial biomass in obese women than in non-obese women, according to a study recently published in Scientific Reports.

High-tech treatment of open leg wounds no better than using regular dressings: study

June 12, 2018
A new study of open leg fractures suggests there is no difference to patient recovery whether high-tech negative pressure wound therapy devices are used, compared to standard dressings.

Risk of post-cesarean infection up for overweight, obese

September 26, 2012
(HealthDay)—About 10 percent of U.K. women who undergo cesarean section develop a surgical site infection, with the odds significantly increased for overweight or obese women, according to a study published in the October ...

Recommended for you

Early postpartum opioids linked with persistent usage

December 14, 2018
Vanderbilt researchers have published findings indicating that regardless of whether a woman delivers a child by cesarean section or by vaginal birth, if they fill prescriptions for opioid pain medications early in the postpartum ...

Hysterectomy linked to memory deficit in an animal model

December 6, 2018
By age 60, one in three American women have had a hysterectomy. Though hysterectomy is a prevalent and routine surgery, the removal of the uterus before natural menopause might actually be problematic for cognitive processes ...

Obesity intervention needed before pregnancy

December 6, 2018
New research from the University of Adelaide's Robinson Research Institute supports the need for dietary and lifestyle interventions before overweight and obese women become pregnant.

First baby born via uterus transplanted from dead donor

December 5, 2018
In a medical first, a mother who received a uterus transplant from a dead donor gave birth to a healthy baby, researchers reported Wednesday.

Researchers find evidence of prenatal environment tuning genomic imprinting

December 5, 2018
A team of researchers from the U.S., Australia and Denmark has found evidence of the prenatal environment tuning genomic imprinting. In their paper published in Proceedings of the National Academy of Sciences, the group describes ...

RSV study reveals age when infants are most vulnerable to asthma

December 5, 2018
New research suggests a maternal vaccination against RSV should be augmented with active immunisation in a child's first two years to reduce the onset of asthma.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.