Advanced alcohol-related liver disease on rise in US, study finds

liver
Credit: CC0 Public Domain

The most deadly forms of alcohol-related liver disease appear to be on the rise in the U.S., a new study finds.

The new research published Tuesday in the Journal of the American Medical Association looked at more than 34,000 people and found the prevalence of alcoholic fatty disease, or AFLD, with at least Stage 2 fibrosis increased from 0.6% in 2001 to 1.5% in 2016.

The incidence of AFLD with Stage 3 or greater fibrosis increased from 0.1% to 0.2%.

"This is a particularly concerning observation given that developing is the strongest predictor of progression to , and death," the study co-authored by Dr. Robert J. Wong at the Alameda Health System–Highland Hospital in Oakland, Calif., said.

The study also cited evidence of an increasing number of cirrhosis deaths, largely driven by alcoholic cirrhosis, particularly among individuals aged 25 to 34 years.

"I think what triggered me to do this study was seeing a lot of patients with advanced alcoholic fatty liver disease," Dr. Wong told NBC News.

Alcoholic liver disease is a leading cause of death in the United States, with nearly 250,000 deaths attributed to the disease in 2010.

One expert told NBC News that binge drinking among younger Americans might be fueling the problem.

"There have been studies in the last few years that suggest that amongst millennials, about 40% will report binge drinking in the past month," Dr. Elliot Tapper, a liver specialist and assistant professor at the University of Michigan, said.

"That means it's basically become a part of the culture for the American millennial. There's no historical precedent for that," he said.

Tapper said binge drinking seven to 14 drinks intermittently is far worse for the liver than drinking one to two drinks per day on a consistent basis.


Explore further

High rates of liver disease progression and mortality observed in patients with NAFLD/NASH

©2019 New York Daily News
Distributed by Tribune Content Agency, LLC.

Citation: Advanced alcohol-related liver disease on rise in US, study finds (2019, May 8) retrieved 17 August 2019 from https://medicalxpress.com/news/2019-05-advanced-alcohol-related-liver-disease.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
1 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more