Cervical cancer rates stable or trending down in countries with effective screening measures

cervical cancer
High grade dysplasia (carcinoma in situ) in the uterine cervix. The abnormal epithelium is extending into a mucus gland to the left of centre. This disease can progress to invasive cancer (squamous cell carcinoma) of the cervix. Credit: Haymanj/public domain

A recent trend analysis indicates that cervical cancer incidence and mortality rates have remained stable or are dropping in most countries across the globe. These rates differ based on each country's socioeconomic development level, cervical cancer screening use, and human papillomavirus (HPV) vaccination rates. The findings are published by Wiley early online in Cancer, a peer-reviewed journal of the American Cancer Society.

Cervical cancer is a potentially preventable disease, through screening to detect and treat and through vaccination against HPV. To reveal the most recent global patterns and trends of , a team led by Mingjuan Jin, Ph.D., of the Zhejiang University School of Medicine in China, examined information released by the International Agency for Research on Cancer pertaining to 31 countries.

The researchers found that cervical cancer incidence and were lower in more socioeconomically developed countries. Also, both past and predicted trends appear to be stable or decreasing in most countries, especially in those with effective cervical cancer screening and HPV vaccination programs.

Over the most recent 10 years, 12 countries had stable cervical cancer incidence rates, 14 had decreasing rates, and five had increasing rates. In terms of mortality from cervical cancer, 12 countries had stable rates, 18 had decreasing rates, and one had an increased rate.

In predictions over the next 15 years for 27 countries, most are expected to have stable or decreasing trends. Ten are predicted to have stable incidence rates, nine to have decreasing rates, and eight to have increasing rates. For mortality from cervical cancer, 16 are predicted to have stable rates, 10 to have decreasing rates, and one to have an increasing rate.

"Effective cervical cancer screening programs and HPV vaccination should be further popularized to increase their coverage and ultimately decrease cervical 's short-, mid-, and long-term burden," said Dr. Jin.


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More information: Shujuan Lin et al, Worldwide trends in cervical cancer incidence and mortality, with predictions for the next 15 years, Cancer (2021). DOI: 10.1002/cncr.33795
Journal information: Cancer

Provided by Wiley
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