Isotretinoin does not up suicide risk in acne patients

Isotretinoin does not up suicide risk in acne patients

(HealthDay)—Acne patients prescribed isotretinoin are less likely to engage in suicidal behavior than the general U.S. population, according to a study published in the Journal of the American Academy of Dermatology.

Nkemjika Ugonabo, M.D., from New York University in New York City, and colleagues used the IBM MarketScan Research Databases to identify acne patients who were prescribed isotretinoin or oral antibiotics between 2011 and 2017. Rates of subsequent psychiatric disorder diagnoses or suicidal behavior were assessed. The analysis included 72,555 patients.

The researchers found that patients in the were more likely to be diagnosed with suicidal ideation or attempt compared with acne patients prescribed isotretinoin (adjusted odds ratio, 1.47). Compared with acne patients prescribed isotretinoin, the general population (adjusted odds ratio, 0.87) and acne patients prescribed antibiotics (adjusted odds ratio, 0.88) were less likely to have a psychiatric diagnosis. During isotretinoin treatment, the prevalence of was lower (0.10 percent) than in the year prior to isotretinoin treatment (0.22 percent) and in the year after treatment (0.34 percent).

"This study found no evidence of increased or of in patients treated with isotretinoin compared to those treated with antibiotics only or those in the general population," the authors write.

One author disclosed serving as a board member of Almirall and as an advisor to Unilever.


Explore further

AAD: isotretinoin exposure for acne not linked to depression risk

More information: Abstract/Full Text (subscription or payment may be required)

Copyright © 2021 HealthDay. All rights reserved.

Citation: Isotretinoin does not up suicide risk in acne patients (2021, September 15) retrieved 25 October 2021 from https://medicalxpress.com/news/2021-09-isotretinoin-suicide-acne-patients.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
20 shares

Feedback to editors