Cells' 'exosomes' may improve the delivery of anticancer drugs to tumors

Credit: Unsplash/CC0 Public Domain

A new study published in Cancer Medicine indicates that exosomes, or small bubbles that transport molecules from one cell to another, can be effective vehicles for delivering cancer treatments to tumors.

In the study, researchers used exosomes produced by called adipose-derived (ADSCs) to deliver an RNA-based anti-cancer treatment (miR-138-5p) to bladder cancer tumors in mice.

"The present results reveal that ADSC-derived exosomes are an effective delivery vehicle for small molecule drugs in vivo, and exosome-delivered miR-138-5p is a promising therapeutic agent for bladder cancer treatment," the authors wrote.

Explore further

Exosome nanoporator: A nanofluidic device to develop exosome-based drug delivery vehicles

More information: Evaluating adipose-derived stem cell exosomes as miRNA drug delivery systems for the treatment of bladder cancer, Cancer Medicine (2022). DOI: 10.1002/cam4.4745
Journal information: Cancer Medicine

Provided by Wiley
Citation: Cells' 'exosomes' may improve the delivery of anticancer drugs to tumors (2022, April 20) retrieved 6 July 2022 from https://medicalxpress.com/news/2022-04-cells-exosomes-delivery-anticancer-drugs.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Feedback to editors