This article has been reviewed according to Science X's editorial process and policies. Editors have highlighted the following attributes while ensuring the content's credibility:


peer-reviewed publication

reputable news agency


Healthy lifestyle does not entirely offset risks for obesity, study finds

Healthy lifestyle does not entirely offset risks for obesity

Adherence to a healthy lifestyle is associated with a lower risk for a wide range of obesity-related diseases, but this association was modest in adults with obesity, according to a study published online May 26 in JAMA Network Open.

Nathalie Rassy, Ph.D., from Hôpital Européen Georges Pompidou in Paris, and colleagues examined the association between healthy lifestyle factors and the incidence of major obesity-related diseases in adults with obesity versus those with normal weight. The analysis included 438,583 U.K. Biobank participants (aged 40 to 73 years) with no major obesity-attributable disease at baseline, followed for 12.8 years. Healthy lifestyle factors included not smoking, exercising regularly, no or , and eating a .

The researchers found that compared with adults with obesity and no healthy lifestyle factors, individuals with obesity who met all four healthy lifestyle factors had a lower risk for hypertension (hazard ratio [HR], 0.84), (HR, 0.72), arrhythmias (HR, 0.71), (HR, 0.65), arteriosclerosis (HR, 0.19), kidney failure (HR, 0.73), gout (HR, 0.51), sleep disorders (HR, 0.68), and mood disorders (HR, 0.66). The lowest risks were associated with the following lifestyle profiles: a healthy diet and physical activity and never smoking. Adults with obesity had a higher risk for several outcomes, irrespective of the lifestyle score, with adjusted HRs ranging from 1.41 for arrhythmias to 7.16 for diabetes for adults with obesity and four healthy lifestyle factors compared with adults with normal weight.

"The findings suggest that although a seems to be beneficial, it does not entirely offset the health risks associated with obesity," the authors write.

More information: Nathalie Rassy et al, Association of Healthy Lifestyle Factors and Obesity-Related Diseases in Adults in the UK, JAMA Network Open (2023). DOI: 10.1001/jamanetworkopen.2023.14741

Journal information: JAMA Network Open

2023 HealthDay. All rights reserved.

Citation: Healthy lifestyle does not entirely offset risks for obesity, study finds (2023, June 1) retrieved 22 September 2023 from
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

People with genetic predisposition to obesity may have lower risk of cardiovascular disease


Feedback to editors