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Study of fevers in children during COVID-19 raises further questions

child fever
Credit: Pixabay/CC0 Public Domain

An uptick in fevers detected among children at more than two dozen hospitals in North America during COVID-19 highlights the question whether there are normally more autoinflammatory disorders such as recurrent fevers among children going overlooked in non-pandemic times, according to a new study by researchers including a CDI physician-scientist.

The paper "Increase in pediatric recurrent evaluations during the first year of the COVID-19 pandemic in North America" was published by Frontiers in Pediatrics, and includes Sivia Lapidus, M.D., pediatric rheumatologist, Joseph M. Sanzari Children's Hospital, Hackensack Meridian Health, the Hearst Foundation Physician-Scientist at the Hackensack Meridian Center for Discovery and Innovation (CDI), and an assistant professor of Pediatrics at the Hackensack Meridian School of Medicine.

"The increase in new patients evaluated for recurrent fevers also suggests that recurrent fevers in may be more common than previously thought and perhaps did not prompt early medical attention pre-pandemic as they were attributed to common infections of childhood," conclude the authors, from the Childhood Arthritis and Rheumatology Research Alliance (CARRA) PFAPA/Autoinflammatory Disease Working Group.

The researchers assessed patient encounters at 27 sites in North America. They found that recurrent fevers jumped from 7.79 percent of pre-pandemic, to 10.9 percent after the arrival of SARS-CoV-2.

Study of fevers in children during COVID-19 raises further questions
Number of new visits with recurrent fever diagnostic codes (absolute number (A) and percentage of all new visits (B)). Credit: Frontiers in Pediatrics (2023). DOI: 10.3389/fped.2023.1240242

"Our data demonstrated a temporal increase in pediatric subspecialty evaluations for new recurrent fever diagnoses during the first year of the COVID-19 pandemic in North America, both in absolute numbers and proportionally in relation with the total new outpatient pediatric encounters in all included in this study," the paper states.

A possible explanation is that fevers normally go overlooked during "normal" times without a pandemic were noticed and prompted a clinical visit during the pandemic, when temperatures were monitored closely.

"We speculate that children with autoinflammatory disorders were recognized earlier because they were having recurrent fevers with minimal infectious exposures from daycare or school, which is consistent with previous reports," they conclude. "Additionally, the frequent assessments of temperature due to COVID-19 precautions may also have increased awareness of childhood recurrent fevers."

"Further research is needed to understand the reasons behind these findings and to explore noninfectious triggers for recurrent fevers in children," they add.

More information: Leanne M. Mansfield et al, Increase in pediatric recurrent fever evaluations during the first year of the COVID-19 pandemic in North America, Frontiers in Pediatrics (2023). DOI: 10.3389/fped.2023.1240242

Provided by Hackensack Meridian Health
Citation: Study of fevers in children during COVID-19 raises further questions (2023, August 29) retrieved 12 June 2024 from https://medicalxpress.com/news/2023-08-fevers-children-covid-.html
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