American Physiological Society

Diseases, Conditions, Syndromes

Better Asthma and COPD Drugs with Fewer Side Effects Are Within Reach

Bronchodilators, the most common type of asthma-fighting drug, inhibits contractions of airway smooth muscle that are induced by stimulating receptors on the muscle's surface. New research highlights a novel mechanism for ...

Medical research

Heat stress prompts kidneys to tap into their reserves

Acute kidney injury—defined as an abrupt decline in glomerular filtration rate (GFR)—is among the top causes of hospitalization during a heat wave. New research published ahead of print in the American Journal of Physiology-Regulatory, ...

Medical research

Faulty neurotransmitter causes weak, overactive bladder in mice

Urinating more frequently and in lower volumes can be a sign of overactive bladder, according to physiologists from Beth Israel Deaconess Medical Center and Harvard Medical School in Boston. Researchers investigated how the ...

Health

New therapeutics could help treat excess urine in the kidneys

Physiologists at the University of Nevada, Reno have identified two ion channels necessary for urine to flow from the kidneys to the ureters. A calcium-activated chloride channel and a voltage-dependent calcium channel are ...

Diseases, Conditions, Syndromes

Inhaling silica particles may cause kidney disease

Amorphous silica is a common mineral used in the manufacturing of products ranging from toothpaste to semiconductors. Though it has generally been considered safe, new research in rats demonstrates that inhaling tiny amorphous ...

Diseases, Conditions, Syndromes

Could loss of smell from COVID-19 create future 'dementia wave?'

A review of studies about the effect of SARS-CoV-2—the virus that causes COVID-19—on the olfactory system introduces questions about whether loss of smell associated with COVID-19 infection may increase the risk of developing ...

Overweight & Obesity

Vitamin B5 activates brown fat, aids weight loss in mice

Pantothenate acid, also known as vitamin B5, stimulated the production of brown fat in both cell cultures and mice, a new study finds. The study is published ahead of print in the American Journal of Physiology-Endocrinology ...

Medications

Marijuana plant might hold key to treating chronic inflammation

Several minor cannabinoids contained in the cannabis plant "strongly inhibit" the activation of human immune cells that lead to chronic inflammation, according to physiologists at The Queen's Medical Center and University ...

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