Babraham Institute

The BBSRC-supported Babraham Institute undertakes international quality life sciences research to generate new knowledge of biological mechanisms underpinning ageing, development and the maintenance of health. The Institute’s research provides greater understanding of the biological events that underlie the normal functions of cells and the implication of failure or abnormalities in these processes. Research focuses on signalling and genome regulation, particularly the interplay between the two and how epigenetic signals can influence important physiological adaptations during the lifespan of an organism. By determining how the body reacts to dietary and environmental stimuli and manages microbial and viral interactions, we aim to improve wellbeing and healthier ageing.

Address
Cambridge CB22 3AT
Website
http://www.babraham.ac.uk/

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Immunology

How to boost immune response to vaccines in older people

Research just published by the Linterman lab shows that the immune system of older mice can be given a helping hand by applying immunology expertise and some genital wart treatment (don't try this at home just yet)!

Oncology & Cancer

Tumor cells' drug addiction may be their downfall

Blocking the processes that drive cancer cell growth is at the heart of many new anti-cancer therapies. Unfortunately, after initial success, cancer cells are generally able to develop workarounds to reactivate the pathways ...

Medical research

How lung tissue forms immune cell hubs in times of need

Immunology researchers at the Babraham Institute have discovered how lung tissue in mice is remodelled in response to infection with influenza in order to support an immune system response. A key result of this tissue remodelling ...

Genetics

Kick-starting the genome in early development

After the fertilisation of an egg cell, two become one; two sets of genetic information combine to form a genome. We can think of the egg and sperm as information capsules with stored instructions for starting a new life, ...

Medical research

Phat on potential, lipidomics is gaining weight

The post-holiday New Year might not seem like an ideal time to celebrate fat. But when it comes to lipids, there is no better time. For the past 15 years, scientists have been working to specify and classify these fatty acids ...

Oncology & Cancer

Breaking through a tumor's defenses

In research published today, Babraham Institute researchers have shown that some tumours use not one but two levels of protection against the immune system. Knocking out one level boosted the protective effects of the second ...

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