Inside brain cells, errors in DNA can accumulate as we age. But in patients with Alzheimer's disease, these errors—known as somatic mutations—may build up at a faster rate. A new study by investigators from Brigham and ...
Apr 20, 2022
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A person's risk of developing diseases such as type 2 diabetes or breast cancer may be influenced by thousands of genetic differences. Looking at a single DNA difference that has a small effect on risk may not be clinically ...
Apr 18, 2022
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85
Headaches such as migraine are among the leading causes of morbidity worldwide, but most treatments provide only partial relief. While scientists know that migraine and related headaches are caused by activity in a part of ...
Mar 28, 2022
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Investigators at the Brigham and the Broad Institute have created specialized, tissue-like structures in the laboratory to model barrier tissues, such as the intestines, to identify new targets for treatment. Barrier tissues ...
Mar 22, 2022
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Inhaled cortical steroids (ICS) can help patients manage asthma symptoms, and recent updates to asthma treatment guidelines have expanded recommended, low-dose treatment. But concerns persist that ICS may reduce production ...
Mar 21, 2022
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171
Heart transplantation can be a lifesaving operation for patients with end-stage heart failure. However, many patients experience organ transplant rejection, in which the immune system begins attacking the transplanted organ. ...
Mar 21, 2022
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Over-the-counter (OTC) analgesics, such as aspirin, non-steroidal anti-inflammatory drugs (NSAIDS), and acetaminophen, are some of the most commonly used medications, widely available without a prescription, and perceived ...
Feb 9, 2022
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163
Autoimmune diseases (AD) such as rheumatoid arthritis, polymyalgia rheumatica, autoimmune thyroid disease and psoriasis, are a leading cause of morbidity and mortality as people age. Few effective treatments are available ...
Jan 26, 2022
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Nearly 80 percent of deaths from type 2 diabetes mellitus (T2DM) are associated with thrombosis, a condition that occurs when blood clots block a vein or artery. Traditionally, it's been thought that proteins released by ...
Jan 10, 2022
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132
Imagine going to the doctor's office at age 55 and, after measuring a set of health variables, the physician predicted your health trajectory for 10 years into the future. Investigators from Brigham and Women's Hospital studied ...
Jan 10, 2022
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