Scientists have long known that the complement cascade, a set of immune system proteins, protects against infection in the body. But in recent years, researchers have uncovered new roles for the system in the brain, including ...
Mar 30, 2023
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Late last year, thousands of children across the United States were hospitalized with respiratory syncytial virus (RSV), but unlike previous RSV surges, this one affected a larger number of people and a broader range of age ...
Feb 23, 2023
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Researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital have constructed a high-resolution cellular map of Crohn's disease, a chronic condition in which a hyperactive immune system causes ...
Jan 31, 2023
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People vary widely in how we think and behave and in our vulnerability to disease, and that variation can be traced at least in part to our brains. Yet scientists don't know how healthy brains vary from one individual to ...
Dec 16, 2022
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Many diseases affect how cells are spatially organized in tissues, such as in Alzheimer's disease, where amyloid-β proteins clump together to form plaques in the brain. Studying how cells differ in various regions of tissue ...
Dec 8, 2022
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Over the past 15 years, more than 200 sites in the human genome have been linked to risk for coronary artery disease (CAD), the leading cause of death worldwide. Still, researchers don't fully understand how those genomic ...
Dec 7, 2022
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Gene therapies can treat, even potentially cure, certain genetic diseases, but it is challenging to deliver the treatments to the parts of the body where they are needed. Researchers have engineered viruses called adeno-associated ...
Nov 22, 2022
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Less than 2% of the human genome is made up of genes that code for proteins, with the remaining 98% being non-coding and involved in regulating gene expression. Scientists have found many changes in the coding region of the ...
Oct 25, 2022
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Organoids are carefully grown collections of cells in a dish, designed to mimic organ structures and composition better than conventional cell cultures and give researchers a unique view into how organs such as the brain ...
Sep 30, 2022
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Trillions of bacteria and other microbes thrive in our gut microbiomes, and over the last decade, scientists have become increasingly aware of the vital role that they play in creating a healthy gastrointestinal environment. ...
Sep 19, 2022
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