The Broad Institute is a genomic medicine research center located in Cambridge, Massachusetts, United States. Although it is independently governed and supported as a 501(c)(3) nonprofit research organization, the institute is formally affiliated with the Massachusetts Institute of Technology, Harvard University and its affiliated hospitals. The faculty and staff of the Broad Institute include physicians, geneticists, and molecular, chemical, and computational biologists.
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An international consortium of scientists has analyzed protein-coding genes from nearly 46,000 people, linking rare DNA alterations to type 2 diabetes. The study, one of the largest known of its type, includes data from people ...
May 22, 2019
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A landmark study, based on genetic analysis of nearly 65,000 people, has revealed that a person's risk of schizophrenia is increased if they inherit specific variants in a gene related to "synaptic pruning"—the elimination ...
Jan 27, 2016
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Researchers from the Broad Institute and several partnering institutions have taken a closer look at the human genome to learn more about the genetic underpinnings of schizophrenia. In two studies published this week in Nature, ...
Jan 22, 2014
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An international team of researchers in Mexico and the United States has uncovered a new genetic clue that contributes to an increased risk of developing type 2 diabetes, particularly the elevated risk among Mexican and other ...
Dec 25, 2013
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Researchers from the Boston area, Mexico, and Norway have completed a comprehensive genomic analysis of cervical cancer in two patient populations. The study identified recurrent genetic mutations not previously found in ...
Dec 25, 2013
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In post-traumatic stress disorder (PTSD), intrusive thoughts, changes in mood, and other symptoms after exposure to trauma can greatly impact a person's quality of life. About 6% of people who experience trauma develop the ...
21 hours ago
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Changes in the gut microbiome have been implicated in a range of diseases including type 2 diabetes, obesity, and inflammatory bowel disease. Now, a team of researchers at the Broad Institute of MIT and Harvard along with ...
Apr 2, 2024
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Researchers have developed statistical tools called polygenic risk scores (PRSs) that can estimate individuals' risk for certain diseases with strong genetic components, such as heart disease or diabetes. However, the data ...
Mar 20, 2024
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Malaria prevalence has decreased drastically over the past two decades, but clinics in West Africa are still full of patients with fevers and symptoms similar to, but not exactly like, malaria.
Mar 11, 2024
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Researchers from the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have uncovered a strikingly similar suite of changes in gene activity in brain tissue from people with schizophrenia and ...
Mar 6, 2024
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