Broad Institute of MIT and Harvard

Oncology & Cancer

Tumors hide from the immune system with help from this protein

Cancer drugs called immune checkpoint inhibitors boost the immune system's ability to find and destroy tumor cells, but they don't work for most patients. Researchers at the Broad Institute of MIT and Harvard, Massachusetts ...

Diseases, Conditions, Syndromes

How B cells fight the COVID-19 virus

A study of antibody-producing B cells from patients who recovered from COVID-19 reveals a new cross-reactive antibody and what makes some B cells more effective at neutralizing the virus.

Oncology & Cancer

New maps link thousands of genetic variants to disease genes

Genome-wide association studies (GWAS) have identified thousands of genetic variants that are associated with a wide range of diseases. But these studies often fall short of establishing what a genetic variant does to bring ...

Oncology & Cancer

Pediatric cancers have unique genetic vulnerabilities

Most cancer drugs that target specific genetic mutations are designed for adult cancers rather than those in children, partly because pediatric cancers have fewer mutations. To look for more ways to target childhood cancers, ...

Neuroscience

Cellular connections found between nervous and immune systems

The nervous and immune systems have long been thought to be separate entities in the body, but new research has uncovered a direct cellular interaction between the two. Scientists from Harvard Medical School, the Broad Institute ...

Oncology & Cancer

Map shows how cancer cells spread through the body

The vast majority of cancer deaths are attributed to metastasis, or the spread of tumors from one organ to another. Determining if a cancer will metastasize has been all but impossible, but if it does, it becomes more difficult ...

Diseases, Conditions, Syndromes

How a lung injury study helped inspire new COVID-19 drug trials

When Anna Greka, an institute member at the Broad Institute of MIT and Harvard and a physician at Brigham and Women's Hospital, volunteered to help care for patients with COVID-19 at the peak of Boston's springtime surge, ...

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