The Buck Institute for Research on Aging is the United States' first independent biomedical research institute devoted solely to research on aging and age-related disease. The mission of the Buck Institute is to extend the healthspan, the healthy years of life. The Institute, a nonprofit organization located in Novato, California, began its research program in 1999. It is named for Marin County philanthropists Leonard and Beryl Buck, whose estate funded the generous endowment that helped establish the Institute, and the Buck Trust currently contributes approximately $6 million annually to support the Institute's work. In May 2007, the Institute established a cooperative agreement with the University of California's Davis and Merced campuses to coordinate stem-cell research, a move hailed by UC as a collaboration that "strengthens California's leadership in stem cell research and moves it forward in an efficient, safe and cost-effective manner." The Institute was designed by architect I.M. Pei who submitted an unsolicited proposal to design the research facility.
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Patient one had two years of progressive memory loss. She was considering quitting her job, which involved analyzing data and writing reports, she got disoriented driving, and mixed up the names of her pets. Patient two kept ...
Oct 1, 2014
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Ibuprofen, a common over-the-counter drug used to relieve pain and fever, could hold the keys to a longer healthier life, according to a study by researchers at the Buck Institute for Research on Aging. Publishing in PLoS ...
Dec 18, 2014
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The major genetic risk factor for Alzheimer's disease (AD), present in about two-thirds of people who develop the disease, is ApoE4, the cholesterol-carrying protein that about a quarter of us are born with. But one of the ...
Oct 21, 2013
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Based on research in fruit flies, it has long been suspected that the most common mutation linked to both sporadic and familial Parkinson's disease (PD) wreaks its havoc by altering the function of mitochondria in neurons ...
Apr 2, 2015
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Dermatologists have long known that available treatments for chronic itch, including eczema, are simply not up to scratch. But scientists have now discovered a new gene that promotes itch, suggesting a way forward for powerful ...
Jun 11, 2015
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Impaired activation of mitochondrial energy metabolism in the presence of glucose has been demonstrated in pancreatic beta-cells from patients with type 2 diabetes. The cause of this dysfunction has been unknown. Publishing ...
Jul 29, 2015
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Low-dose lithium reduced involuntary motor movements - the troubling side effect of the medication most commonly used to treat Parkinson's disease (PD) - in a mouse model of the condition that is diagnosed in about 60,000 ...
Jul 27, 2015
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Johns Hopkins researchers, working with an international consortium, say they have generated stem cells from skin cells from a person with a severe, early-onset form of Huntington's disease (HD), and turned them into neurons ...
Jun 28, 2012
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Intermittent dosing with rapamycin selectively breaks the cascade of inflammatory events that follow cellular senescence, a phenomena in which cells cease to divide in response to DNA damaging agents, including many chemotherapies. ...
Jul 6, 2015
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Rapamycin, an FDA-approved drug, extends lifespan in mice up to 30%, making it of major interest to researchers intent on slowing the aging process in humans in order to extend healthspan, the healthy years of life. But long ...
Feb 9, 2015
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