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While the role of the blood-brain barrier has long been appreciated for its ability to maintain precise control over what molecules can enter the nervous system, very little is known about how the cells that form the barrier ...
Aug 15, 2022
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While newly approved drugs for Alzheimer's show some promise for slowing the memory-robbing disease, the current treatments fall far short of being effective at regaining memory. What is needed are more treatment options ...
Feb 1, 2024
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Restricting calories is known to improve health and increase lifespan, but much of how it does so remains a mystery, especially in regard to how it protects the brain. Buck Institute for Research on Aging scientists have ...
Jan 11, 2024
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Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process.
Nov 13, 2023
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A woman's fertility normally decreases by her late 30s with reproductive function eventually ceasing at menopause. It is known that a small molecule called nicotinamide adenine dinucleotide (NAD+) plays a critical role in ...
Oct 18, 2023
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Humans lose brain volume as they age, at an estimated rate of 5% per decade after age 40. But that estimate obscures the role that individual physiology plays in regards to functional brain aging.
Dec 6, 2022
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The immune system protects us from infections, harmful substances and problematic changes in our own cells. Traditional research posits that parts of invading pathogens or cells sound the alarm, but accumulating evidence ...
Aug 16, 2022
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Researchers from the Buck Institute have demonstrated for the first time a link between diet, circadian rhythms, eye health and lifespan in Drosophila. Publishing in the June 7, 2022 issue of Nature Communications, they additionally ...
Jun 7, 2022
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Utilizing cutting-edge proteomics, researchers at the Buck Institute and elsewhere have mapped the "tau interactome" uncovering new findings about the role of tau in neurodegenerative disease. Publishing in Cell, scientists ...
Jan 20, 2022
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Researchers from the Buck Institute and Stanford University have created an inflammatory clock of aging (iAge) which measures inflammatory load and predicts multi-morbidity, frailty, immune health, cardiovascular aging and ...
Jul 12, 2021
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