Children's Hospital Boston

Medical research

Researchers grow hairy skin from human stem cells

For more than 40 years, scientists and commercial companies have been recreating human skin in laboratories around the world. Yet all of these products lack important aspects of normal skin—hair, nerves, and fat.

Medical research

Could leukemia be stopped before it starts?

Acute myeloid leukemia (AML), a blood cancer affecting both adults and children, requires more than one genetic "hit" to develop. As we age, many of us acquire a mutation that enables certain of our blood cells to multiply ...

Health

School obesity-prevention curriculum can reduce medical costs

Teaching middle-school children about nutrition and exercise and encouraging them to watch less TV can save the health care system a substantial amount of money, suggests an economic analysis from Children's Hospital Boston ...

Oncology & Cancer

A cancer's surprise origins, caught in action

Researchers at Boston Children's Hospital have, for the first time, visualized the origins of cancer from the first affected cell and watched its spread in a live animal. Their work, published in the January 29th issue of ...

Arthritis & Rheumatism

Why inflammatory arthritis always recurs in certain joints

When joints flare up in people with rheumatoid arthritis and related diseases, the joints involved are often the same as those affected before. For example, if arthritis started in the right knee, it is much more likely to ...

Genetics

Rare recessive mutations pry open new windows on autism

Over the past decade, autism spectrum disorder has been linked to mutations in a variety of genes, explaining up to 30 percent of all cases to date. Most of these variants are de novo mutations, which are not inherited, affect ...

Immunology

How do cells release IL-1? After three decades, now we know

Researchers at Boston Children's Hospital have identified, for the first time, the molecule that enables immune cells to release interleukin-1 (IL-1), a key part of our innate immune response to infections. Findings were ...

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