Children's Hospital Boston

Diseases, Conditions, Syndromes

Type III interferons: Protective or harmful in COVID-19?

Interferons and other cytokines produced by the immune system are important defenses against viral infections, but as we have seen in COVID-19, they can also contribute to damaging, potentially life-threatening lung inflammation. ...

Neuroscience

Why does fasting reduce seizures?

Calorie restriction has long been associated with reduced seizures in epilepsy. New research from Boston Children's Hospital helps explain how fasting affects neurons in the brain and could lead the way to new approaches ...

Genetics

GIANT study reveals giant number of genes linked to height

The largest genome-wide association study (GWAS) to date, involving more than 300 institutions and more than 250,000 subjects, roughly doubles the number of known gene regions influencing height to more than 400. The study, ...

Neuroscience

Creating custom brains from the ground up

Scientists studying how genetics impact brain disease have long sought a better experimental model. Cultures of genetically-modified cell lines can reveal some clues to how certain genes influence the development of psychiatric ...

Neuroscience

Lab-grown human cerebellar cells yield clues to autism

Increasing evidence has linked autism spectrum disorder (ASD) with dysfunction of the brain's cerebellum, but the details have been unclear. In a new study, researchers at Boston Children's Hospital used stem cell technology ...

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