Cincinnati Children's Hospital Medical Center

Immunology

Scientists discover how gene mutation triggers immune disease

Scientists discovered how a gene mutation affects T cell function to promote immune disorders and then tested a treatment based on the discovery—successfully fixing donated immune cells from a 16-year-old boy with an abnormally ...

Medical research

Study identifies unexpected clue to peripheral neuropathies

New research shows that disrupting the molecular function of a tumor suppressor causes improper formation of a protective insulating sheath on peripheral nerves – leading to neuropathy and muscle wasting in mice similar ...

Genetics

Scientists find molecular key to body making healthy T cells

In a finding that could help lead to new therapies for immune diseases like multiple sclerosis and IBD, scientists report in the Journal of Experimental Medicine identifying a gene and family of proteins critical to the formation ...

Medical research

Room for improvement in drug dosage timing in hospitals

Too many hospitals provide medications according to the practicalities of their staffing schedules rather than the ideal dosing times for their patients, according to a new study led by experts at Cincinnati Children's.

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