Cold Spring Harbor Laboratory

Oncology & Cancer

Milestone reached in new leukemia drug

Cold Spring Harbor Laboratory scientists, with chemists and cancer biologists from Dana-Farber Cancer Institute (DFCI), have developed a new therapy that extended the survival of mice with acute myeloid leukemia.

Neuroscience

The difference between an expert's brain and a novice's

When mice learn to do a new task, their brain activities change over time as they advance from 'novice' to 'expert.' The changes are reflected in the wiring of cell circuits and activities of neurons.

Neuroscience

BARseq builds a better brain map

Cold Spring Harbor Laboratory Professor Anthony Zador has taken the next step in his quest to solve exactly how the brain is wired.

Neuroscience

New brain research could change how concussions are treated

Traumatic brain injuries (TBI), including concussions, can be caused by anything from sports injuries to battlefield trauma. And they can have fatal or lasting effects. The results of a severe concussion—problems with thinking, ...

Oncology & Cancer

Mutant cells team up to make an even deadlier blood cancer

Sometimes the whole is greater than the sum of its parts. Researchers at Cold Spring Harbor Laboratory have discovered that two cell mutations, already harmful alone, enhance one another's effects, contributing to the development ...

Oncology & Cancer

Discovery could improve MDS cancer treatment

Myelodysplastic syndrome (MDS), one of the most common blood cancers, has very few treatment options. Now, researchers at Cold Spring Harbor Laboratory (CSHL) have discovered a new and promising drug target for this deadly ...

Neuroscience

Mice, like humans, fidget when deep in thought

Almost everyone fidgets, said Cold Spring Harbor Laboratory Associate Professor Anne Churchland. She referred to a collage of videos she compiled of different people rocking back and forth in their chairs, clicking a pen, ...

Oncology & Cancer

Cancer drugs don't always work as intended, researchers warn

Scientists at Cold Spring Harbor Laboratory (CSHL) have identified 10 cancer drugs currently in clinical trials that do not work how clinicians thought they would. In identifying what went wrong, experts can now work to improve ...

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