How close to reality are brain organoids, and which molecular mechanisms underlie the remarkable self-organizing capacities of tissues? Researchers already have succeeded in growing so-called "cerebral organoids" in a dish ...
Mar 10, 2017
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Addiction-related memories are exceptionally strong and stable, suggesting that addictive drugs remodel the brain's circuitry in a prominent and lasting way. In the past decade, researchers have used mouse models to unravel ...
Jan 11, 2017
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A characteristic feature of Alzheimer's disease is the presence of so called amyloid plaques in the patient's brain - aggregates of misfolded proteins that clump together and damage nerve cells. Although the body has mechanisms ...
Dec 21, 2016
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The loss of CHD1, one of the most frequently mutated genes in prostate tumors, sensitizes human prostate cancer cells to different drugs, including PARP inhibitors. This suggests CHD1 as a potential biomarker for targeted ...
Sep 5, 2016
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Researchers at the Ludwig-Maximilians-University, the German Center for Neurodegenerative Diseases (DZNE), and the Institute for Stroke and Dementia Research (ISD) in Munich, Germany, have identified a brain inflammation ...
Mar 3, 2016
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Researchers at King's College London and the Wellcome Trust Sanger Institute in the United Kingdom have for the first time demonstrated a direct link between the Wbp2 gene and progressive hearing loss. The scientists report ...
Feb 8, 2016
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Researchers in Italy, Germany and the United States have identified a regulatory protein crucial for the development of Cerebral Cavernous Malformation – a severe and incurable disease mainly affecting the brain microvasculature. ...
Nov 26, 2015
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Researchers in the United Kingdom and Denmark have studied the "see-through" larvae of zebrafish to reveal how wound healing leads to skin cancer. Live imaging shows neutrophils, the protective inflammatory cells of the body's ...
Jul 1, 2015
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A genetic investigation of individuals in the Framingham Heart Study may prove useful to identify novel targets for the prevention or treatment of high blood pressure. The study, which takes a close look at networks of blood ...
Apr 16, 2015
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Researchers at Harvard Medical School and Columbia University in the United States have developed a way to study the functions of hard-to-grow bacteria that contribute to the composition of the gut microbiome. The new method ...
Mar 11, 2015
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