Friedrich Miescher Institute for Biomedical Research

The Friedrich Miescher Institute for Biomedical Research (FMI) is part of the Novartis Research Foundation and is a world-class center for basic research in life sciences based in Basel, Switzerland. The FMI is devoted to the pursuit of fundamental biomedical research. Areas of expertise are: In these fields the FMI has gained international recognition as a center of excellence in innovative biomedical research. Research is carried out in 22 independent but highly interactive research teams. In addition, seven technology platforms, ranging from functional genomics to microscopy and imaging, support the research activities with cutting-edge technology. As of 2011, the institute counts 320 collaborators of which 90 are postgraduate students participating in the FMI International PhD Program, 100 are postdoctoral collaborators and 22 are research group leaders. Since 2004, the institute is led by Susan M. Gasser. in chronological order The FMI is an affiliated institute of the University of Basel. It provides biomedical research and career training for over 90 PhD students. FMI selects its highly international student body during a twice-yearly interview-based selection program.

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Genetics

Epigenetic regulation of face formation

Each face is unique, even though the genes controlling facial shape are almost identical in every individual. Filippo Rijli and his team at the Friedrich Miescher Institute for Biomedical Research (FMI) have discovered an ...

Medical research

Mechanism of action of thalidomide elucidated

(Medical Xpress)—Scientists led by Nicolas Thomä at the Friedrich Miescher Institute for Biomedical Research have clarified the workings of thalidomide at the molecular level. Their analysis of various structures, published ...

Neuroscience

Controlling anxiety

Researchers at Andreas Lüthi's laboratory have identified a cell type in the brain, which controls anxiety - a complex behavioral state - and have elucidated the underlying mechanisms. These findings thus improve our understanding ...

Neuroscience

Familiar objects can prevent autism-like behaviors in mouse model

The emergence of autism traits can result from different factors, such as a person's environment and genetic background. FMI researchers and their Novartis collaborators showed that exposing mice with an autism mutation to ...

Neuroscience

New function for rods in daylight

(Medical Xpress)—Vision – so crucial to human health and well-being – depends on job-sharing by just a few cell types, the rod cells and cone cells, in our retina. Botond Roska and his group have identified a novel ...

Genetics

Genetic guides to epigenetics

Dirk Schübeler and his group at the Friedrich Miescher Institute for Biomedical Research (FMI) identify determinants that set epigenetic marks along the genome. The new study, published in Nature, shows that genetic activity ...

Neuroscience

How neurons that wire together fire together

For amplifying sensory stimuli quickly and accurately, neuronal circuits require specific wiring. Some 70 years ago, the compelling idea that "neurons that fire together wire together" emerged. Yet, in computational models, ...

Neuroscience

How AI can help uncover the way memory works

Over the past few years, artificial intelligence—or AI—has started to revolutionize the world as we know it: some people now ask AI-based chatbots to write essays and summarize documents, others use AI-powered virtual ...

Genetics

The influence of the mother: Maternal epigenetic inheritance

(Medical Xpress) -- A study published in Genes and Development from scientists at the Friedrich Miescher Institute for Biomedical Research pinpoints the importance of maternal epigenetic influences during early embryogenesis ...

Neuroscience

What you see is not always what you get

Georg Keller and his group at the Friedrich Miescher Institute for Biomedical Research (FMI) have identified neurons in the visual cortex whose activity predicts an upcoming visual stimulus. This activity emerges with experience ...

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