Friedrich Miescher Institute for Biomedical Research

Epigenetic regulation of face formation

Each face is unique, even though the genes controlling facial shape are almost identical in every individual. Filippo Rijli and his team at the Friedrich Miescher Institute for Biomedical Research (FMI) have discovered an ...

Mar 30, 2017
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Controlling anxiety

Researchers at Andreas Lüthi's laboratory have identified a cell type in the brain, which controls anxiety - a complex behavioral state - and have elucidated the underlying mechanisms. These findings thus improve our understanding ...

Sep 23, 2015
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Genetic guides to epigenetics

Dirk Schübeler and his group at the Friedrich Miescher Institute for Biomedical Research (FMI) identify determinants that set epigenetic marks along the genome. The new study, published in Nature, shows that genetic activity ...

Feb 10, 2015
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Mechanism of action of thalidomide elucidated

(Medical Xpress)—Scientists led by Nicolas Thomä at the Friedrich Miescher Institute for Biomedical Research have clarified the workings of thalidomide at the molecular level. Their analysis of various structures, published ...

Jul 17, 2014
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Switching learning on

Neurobiologist from the Friedrich Miescher Institute for Biomedical Research show how a network of neurons in hippocampus and cortex switches states to turn on and off learning in the adult. They further show how a stimulating ...

Dec 12, 2013
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Releasing the neuronal brakes for learning

(Medical Xpress)—Learning can only occur if certain neuronal "brakes" are released. As the group led by Andreas Lüthi at the Friedrich Miescher Institute for Biomedical Research has now discovered, learning processes in ...

May 22, 2014
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Interfering with breast cancer metastasis

(Medical Xpress)—Nancy Hynes and her group at the Friedrich Miescher Institute for Biomedical Research have discovered an important mediator of breast cancer metastasis. The protein called Memo is not only required for ...

Jun 20, 2014
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Transcriptional control of sound discrimination

Filippo Rijli and his team at the Friedrich Miescher Institute for Biomedical Research have identified two genes that control sound discrimination in the brain. The Hox2 transcription factors act in the mouse brain stem and ...

Feb 03, 2017
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Mapping face sensation in the brainstem

Filippo Rijli and his group at the FMI have shown how the formation of a sensory topographic map in the brainstem is controlled by a single transcription factor, thus shedding light on a decades-old question in neuroscience. ...

Oct 23, 2015
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