Friedrich Miescher Institute for Biomedical Research

The Friedrich Miescher Institute for Biomedical Research (FMI) is part of the Novartis Research Foundation and is a world-class center for basic research in life sciences based in Basel, Switzerland. The FMI is devoted to the pursuit of fundamental biomedical research. Areas of expertise are: In these fields the FMI has gained international recognition as a center of excellence in innovative biomedical research. Research is carried out in 22 independent but highly interactive research teams. In addition, seven technology platforms, ranging from functional genomics to microscopy and imaging, support the research activities with cutting-edge technology. As of 2011, the institute counts 320 collaborators of which 90 are postgraduate students participating in the FMI International PhD Program, 100 are postdoctoral collaborators and 22 are research group leaders. Since 2004, the institute is led by Susan M. Gasser. in chronological order The FMI is an affiliated institute of the University of Basel. It provides biomedical research and career training for over 90 PhD students. FMI selects its highly international student body during a twice-yearly interview-based selection program.

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Neuroscience

How AI can help uncover the way memory works

Over the past few years, artificial intelligence—or AI—has started to revolutionize the world as we know it: some people now ask AI-based chatbots to write essays and summarize documents, others use AI-powered virtual ...

Neuroscience

Familiar objects can prevent autism-like behaviors in mouse model

The emergence of autism traits can result from different factors, such as a person's environment and genetic background. FMI researchers and their Novartis collaborators showed that exposing mice with an autism mutation to ...

Neuroscience

How neurons that wire together fire together

For amplifying sensory stimuli quickly and accurately, neuronal circuits require specific wiring. Some 70 years ago, the compelling idea that "neurons that fire together wire together" emerged. Yet, in computational models, ...

Neuroscience

From imaging neurons to measuring their true activity

When neurons communicate with each another, they transmit—or "fire"—small electrical impulses called action potentials or spikes. These action potentials are the fundamental units of information processing in the brain. ...

Inflammatory disorders

Mini-guts reveal crucial forces that shape the intestinal lining

Using miniature guts grown in a dish and 3D biophysical modeling, FMI researchers and their collaborators have uncovered the forces that give the intestinal wall its classic brushlike appearance. The findings can help to ...

Medical research

Brain state behind social interaction uncovered

The brain's emotion-processing center—the amygdala—is one of several brain regions involved in social behavior. But the exact role that this almond-shaped structure plays in the so-called 'social brain' remains mysterious. ...

Neuroscience

Building corticocerebellar neural circuits

In a comprehensive study, researchers from the Rijli group found that a single Hox transcription factor expressed in a group of neurons of the pontine nucleus—the cerebral cortex most important brainstem relay to the cerebellum—determines ...

Medical research

Preventing the onset of schizophrenia in a mouse model

Although predisposing processes occur earlier, schizophrenia emerges at young adulthood, suggesting it might involve a pathological transition during late brain development in predisposed individuals. Using a genetic mouse ...

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