Garvan Institute of Medical Research

Gerontology & Geriatrics

A 'skeletal age' calculator to predict bone fracture risk

Researchers at the Garvan Institute of Medical Research have developed a computational model to calculate 'skeletal age', a personalized estimate of an individual's risk of bone fracture and premature death.

Alzheimer's disease & dementia

Metformin treatment linked to slowed cognitive decline

Metformin is the first-line treatment for most cases of type 2 diabetes and one of the most commonly prescribed medications worldwide, with millions of individuals using it to optimize their blood glucose levels.

Oncology & Cancer

Revealed: How cancer develops resistance to treatment

Cancer cells can turn on error-prone DNA copy pathways to adapt to cancer treatment, a breakthrough study published in the journal Science has revealed. Bacteria use the same process, termed stress-induced mutagenesis, to ...

Immunology

Research pinpoints rogue cells at root of autoimmune disease

There are more than 100 different autoimmune diseases. But what unites them all is that they arise from an individual's own cells—rare and mysterious immune cells that target not external viruses and bacteria but the body's ...

Genetics

Researchers uncover the genomics of health

Most diseases have a genetic component. To better understand disease, researchers led by the Garvan Institute of Medical Research are analysing genetic information to determine what keeps us healthy.

Immunology

Extinct human species gave modern humans an immunity boost

Findings from the Garvan Institute of Medical Research show modern humans acquired a gene variant from Denisovans that heightened their immune reactions, indicating adaptation of the immune system to a changing environment.

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