If you're one of the nearly 25 percent of people with the gene variant known as APOE4, you have a higher-than-average chance of developing Alzheimer's disease. But while scientists have long known that APOE4 leads to changes ...
Oct 20, 2023
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57
When news about a novel coronavirus switched from a chronicle of its progress in China to headlines about a worldwide COVID-19 pandemic, Gladstone Institutes scientist Nadia Roan, Ph.D., was in the midst of publishing several ...
Aug 21, 2020
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158
Scientists at the Gladstone Institutes have identified a finely tuned mechanism by which fetal heart muscle develops into a healthy and fully formed beating heart—offering new insight into the genetic causes of congenital ...
Jan 22, 2012
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Viruses are parasites. The only way they can grow is by hijacking their hosts. When they infect a human host, viruses use human proteins to multiply and modify the human cells to sustain the infection. At the same time, the ...
Feb 20, 2020
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545
Scientists at the Gladstone Institutes and the University of California, San Francisco (UCSF) have successfully converted human skin cells into fully-functional pancreatic cells. The new cells produced insulin in response ...
Jan 6, 2016
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844
A team of Gladstone scientists and their partners at Xyphos Biosciences, Inc. describe a new way of attacking cells infected by HIV in this week's issue of the journal Cell. The work showcases a novel version of CAR-T, the ...
Oct 24, 2019
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14
For the nascent brain of a human embryo to develop into the complex organ that controls human consciousness, a finely tuned sequence of genetic events has to take place; hundreds of genes are activated and deactivated in ...
Jun 30, 2020
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212
Scientists at the Gladstone Institutes have discovered a key protein that regulates insulin resistance—the diminished ability of cells to respond to the action of insulin and which sets the stage for the development ...
Mar 28, 2012
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0
When a coronavirus—including SARS-CoV-2, which causes COVID-19—infects someone, it hijacks the person's cells, co-opting their molecular machinery for its own survival and spread. Researchers at Gladstone Institutes and ...
Dec 8, 2020
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59
A new study from the Gladstone Institutes shows that a single drop of blood in the brain is sufficient to activate an autoimmune response akin to multiple sclerosis (MS). This is the first demonstration that introduction ...
Oct 9, 2015
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