Gladstone Institutes

Immunology

'Natural immunity' from omicron is weak and limited, study finds

In unvaccinated people, infection with the omicron variant of SARS-CoV-2 provides little long-term immunity against other variants, according to a new study by researchers at Gladstone Institutes and UC San Francisco (UCSF), ...

Cardiology

Can a common heart condition cause sudden death?

About one person out of 500 has a heart condition known as hypertrophic cardiomyopathy (HCM). This condition causes thickening of the heart muscle and results in defects in the heart's electrical system. Under conditions ...

Neuroscience

Support cells in the brain offer a new strategy to boost memory

A study by scientists from the Gladstone Institutes shows that decreasing the number of A2A adenosine receptors in a particular type of brain cells called astrocytes improved memory in healthy mice. What's more, reducing ...

Medical research

Overcoming obstacles to promote repair in multiple sclerosis

In the nearly 1 million Americans living with multiple sclerosis, the fatty substance that insulates the nerves of the central nervous system—called myelin—is damaged. This slows the transmission of signals from their ...

Neuroscience

Two possible new ways to treat silent seizures in children

January 2, 2019—As early as 3 months of age, infants with a severe form of epilepsy called Dravet syndrome start having convulsive seizures, during which their arms and legs jerk repeatedly. As they become toddlers, another ...

Alzheimer's disease & dementia

New study reveals how blood triggers brain disease

In patients with neurological diseases like Alzheimer's disease and multiple sclerosis, immune cells in the brain known as microglia that normally fulfill beneficial functions become harmful to neurons, leading to cognitive ...

Medical research

Scientists map the genomic blueprint of the heart

Scientists at the Gladstone Institutes have revealed the precise order and timing of hundreds of genetic "switches" required to construct a fully functional heart from embryonic heart cells—providing new clues into the ...

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