Lung cancer is the second most common cancer in the U.S. and the No. 1 cause of cancer related death. Despite considerable progress in treatment options, most lung cancer patients have extremely poor outcomes with an average ...
Feb 11, 2022
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1096
Endometrial cancer is the most common cancer of the female reproductive system. Patients who have active immune responses against cancer cells tend to have better outcomes, but much of what is known focuses on only one type ...
Jan 12, 2022
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73
Immunotherapy has become an important tool in the treatment of lung cancer, especially checkpoint inhibitors that block certain immune checkpoints to allow immune cells to recognize and kill cancer cells. Several checkpoint ...
Aug 12, 2021
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106
A dysfunctional immune system significantly contributes to the development of cancer. Several therapeutic strategies to activate the immune system to target cancer cells have been approved to treat different types of cancer, ...
Apr 8, 2021
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46
Tumors are genetically diverse with different mutations arising at different times throughout growth and development. Many models have tried to explain how genetic heterogeneity arises and what impact these alterations have ...
Apr 6, 2021
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44
The prognosis of ovarian cancer is poor, with an estimated five-year survival of only 40% for advanced disease, the stage at which most ovarian carcinomas are diagnosed. These poor outcomes are partly due to the lack of effective ...
Feb 3, 2021
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42
Evolution within groups of tumor cells follows the principles of natural selection, as evolution in pathogenic microbes. That is, the diversity of cellular characteristics within a group leads to differences in the ability ...
Jan 21, 2021
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31
Cells need energy to survive and thrive. Generally, if oxygen is available, cells will oxidize glucose to carbon dioxide, which is very efficient, much like burning gasoline in your car. However, even in the presence of adequate ...
Jan 19, 2021
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59
The hallmarks of cancer include rapid cell reproduction and metabolic activity. But these processes also lead to increased cellular stress and oxidation, and the risk of cell death. To circumvent these negative consequences ...
Jan 14, 2021
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75
Personalized treatment options for patients with lung cancer have come a long way in the past two decades. For patients with non-small cell lung cancer, the most common subtype of lung cancer and the leading cause of cancer-related ...
Oct 16, 2020
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45
