Instituto Gulbenkian de Ciencia is located in the Oerias about 20km from Lisbon, Portugal. It was formed to study and research the genetic basis of development, evolution of complex systems, the genetics of complex human disease, and includes privileging organism centered approaches in experimental models that includes, plants, yeast, flies, and mice for the purpose of studying human disease. The BioInformatics, Cell Imaging, and Chemical and Biological Technology institutes are among the research centers of IGC Gulbenkian. It is the home to post-doctoral fellows, scientists working on individual research programs.
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Weight is controlled by the hormone leptin, which acts in the brain to regulate food intake and metabolism. However, it was largely unknown until now, how the brain signals back to the fat tissue to induce fat breakdown. ...
Sep 24, 2015
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The latest issue of the journal Cell carries an article that is likely to help solve one of the long-standing mysteries of biomedicine. In a study that challenges currently held views, researchers at the Instituto Gulbenkian ...
Apr 28, 2011
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A research team led by Ana Domingos, from Instituto Gulbenkian de Ciencia (IGC; Portugal) has developed a new genetic technique that eliminates specific neurons of the peripheral nervous system without affecting the brain. ...
Apr 3, 2017
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A group of scientists from Instituto Gulbenkian de Ciência (IGC), led by Luís Moita, discovered that a hormone that has been pointed out as a treatment for obesity reduces the resistance to infection caused by bacteria ...
Jun 22, 2020
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The biological causes underlying obesity have been under intense scrutiny, with studies suggesting a link between the nervous and the immune systems. Now, in a breakthrough study to be published in Nature Medicine on 9 October, ...
Oct 9, 2017
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The prevalence of obesity, a disease considered a serious public health problem, is increasing globally. In Portugal, almost half of the population is overweight and close to one million adults suffer from obesity. Known ...
Jan 10, 2020
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The immune system protects from infections by detecting and eliminating invading pathogens. These two strategies form the basis of conventional clinical approaches in the fight against infectious diseases. In the latest issue ...
Feb 23, 2012
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New versions of genes, called alleles, can appear by mutation in populations. Even when these new alleles turn the individuals carrying them more fit to survive and reproduce, the most likely outcome is that they will get ...
Sep 13, 2013
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One of the major therapeutic targets for inflammatory diseases is the inflammation-inducing molecule TNF. However, excess levels of TNF cause side effects and can lead to diseases. In a study now published in eLIFE, the research ...
Jul 27, 2018
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Our gut is inhabited by a diverse community of microbes, the gut microbiota. This community, composed of hundreds of different species, is essential to our health: it influences our immune system, protects us from infections, ...
Jan 26, 2022
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