Josep Carreras Leukaemia Research Institute is an International Research Institute whose mission is to investigate fundamental, epidemiological, preventive, clinical and translational aspects of leukemia, lymphoma, and other hematologic malignancies.
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The simplest explanation of cancer is that, for any reason, a cell in our body ignores its biological program and gets loose, multiplying itself again and again, creating a tumor. This has a lot to do with the wrong use of ...
Apr 5, 2024
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There are many anti-cancer genes that are no longer active in human tumors, preventing them from carrying out their protective function against cell transformation. One of the main mechanisms used by cancer cells to silence ...
Mar 14, 2024
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Alterations in the chemical modifications that control gene expression, known as epigenetics, have proven to be one of the most characteristic properties of all human tumors. This realization has generated the development ...
Feb 5, 2024
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COVID-19 became an international pandemic in 2020. To date, more than 770 million people have suffered from the disease and nearly 7 million of them have lost their life. The most common cause of death in the studied group ...
Nov 14, 2023
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The immune system is one of the most complex parts of our body. It keeps us healthy by getting rid of parasites, viruses or bacteria, and by destroying damaged or cancer cells. One of its most intriguing abilities is its ...
Jul 13, 2023
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Researchers at the Josep Carreras Leukemia Research Institute, led by Dr. Manel Esteller, have discovered a key epigenetic alteration that anticipates the clinical course of liver cancer. This is the deactivation of the NSUN7 ...
May 16, 2023
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The oncogenic activation of MYC, a critical gene in cancer progression, has the potential to identify lung cancer patients who may respond poorly to immunotherapy (ICB). This is the main conclusion of a study recently published ...
Apr 14, 2023
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For a long time, cancer genetics and epigenetics researchers have been focusing on alterations in genes and proteins to understand what makes a cell turn cancerous and become malignant. In the nucleus of the cell, there is ...
Jan 25, 2023
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Researchers of the Hospital Universitario 12 de Octubre in Madrid and the Josep Carreras Leukaemia Research Institute in Barcelona have developed a cell therapy for a type of leukemia which currently has very few treatment ...
Jan 16, 2023
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In the early 1980s, the first changes in DNA related to a chemical modification called methylation were discovered, followed by the discovery in the mid-1990s of the first tumor suppressor genes inactivated by these modifications ...
Dec 22, 2022
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