Malaria remains a deadly disease that affects people worldwide, particularly in Africa. Caused by a parasite that can enter the human bloodstream via mosquito bite, the parasites can then infect and reproduce within the person's ...
Sep 16, 2021
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The RB1 tumor suppressor gene protein antagonizes uncontrolled growth of cancer by suppressing cell cycle progression but its function is repressed in most cancers. CDK4/6 represses this function by phosphorylating RB1. In ...
Sep 2, 2021
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Interluekin-1α (IL-1α) is an important part of the immune response, but until now it has been unclear how this molecule is processed from its precursor, pro-IL-1α, and exits the cell during inflammasome activation. Now, ...
Jun 18, 2021
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Our bodies and behaviors often seem to have rhythms of their own. Why do we go to the bathroom at the same time every day? Why do we feel off if we can't go to sleep at the right time? Circadian rhythms are a behind-the-scenes ...
Apr 28, 2021
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Chronic lower-limb edema (CLE)—the permanent accumulation of fluid in the leg—often occurs in elderly people. The condition leads to various physical and mental problems, including difficulty in walking or moving, fatigue ...
Apr 19, 2021
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As the global population ages, the rate of dementia is increasing worldwide. Given that early detection is critical for treatment, effective ways to screen for dementia are a high research priority. Now, researchers from ...
Mar 5, 2021
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Most tumors consist of a heterogenous mix of cells. Genetic mutations found only in some of these cells are known to aid with the spread and progression of cancer. However, oncologists often find that when tumors metastasize ...
Feb 12, 2021
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The human body consists of about 60 trillion cells that are renewed day by day to maintain homeostasis of body tissues. In particular, cells of the digestive tract are renewed completely within several weeks thanks to vigorous ...
Feb 8, 2021
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Most lung cancers are of a type called non-small-cell lung carcinoma (NSCLC). This type of cancer is relatively insensitive to chemotherapy, so NSCLC therapies are usually based on drug treatment. Alectinib is a drug commonly ...
Jan 22, 2021
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Liver injury is a rare side effect of nonsteroidal anti-inflammatory drugs (NSAIDs), which are frequently used for daily pain control. This toxicity has been regarded as a 'black box' and is mainly managed by an empirical ...
Jan 22, 2021
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