Kumamoto University, abbreviated to Kumadai, is a Japanese national university located in Kumamoto, Kumamoto prefecture in the Kyushu region of Japan. It was established on May 31, 1949, at which time the following institutions were subsumed into it; Kumamoto Teachers College (established in 1874), Kumamoto Pharmaceutical College (1885), the Fifth High School (1887), Kumamoto Medical College (1896), and Kumamoto Technical College (1906).
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The processes of DNA replication and transcription may introduce torsional (or twisting) strains in the DNA structure. These topological problems are relieved by an enzyme called topoisomerase II (TOP2) via a series of reactions.
Jan 18, 2023
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A research collaboration based in Kumamoto University, Japan has discovered that muscles and the resident stem cells (satellite cells) responsible for muscle regeneration retain memory of their location in the body. This ...
Jul 6, 2021
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Researchers at Kumamoto University, Japan, have generated mice lacking the estrogen receptor beta (ERβ) gene, both fiber-specific and muscle stem cell-specific, which resulted in abnormalities in the growth and regeneration ...
Oct 13, 2020
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A research collaboration between Kumamoto University and Nagasaki University in Japan has found that components leaking from broken muscle fibers activate "satellite" muscle stem cells. While attempting to identify the proteins ...
Oct 13, 2020
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Research from Kumamoto University, Japan finds that a natural compound isolated from onions, onionin A (ONA), has several anti-cancer properties for ovarian cancer. This discovery is a result of research on the effects of ...
Oct 21, 2016
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Type 2 diabetes (T2D) is characterized by persistent hyperglycemia (high glucose in blood) that leads to hypoxia (low oxygen condition) in pancreatic β-cells.
Sep 20, 2023
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Tumor-initiating cells, or cancer stem cells, are gaining attention in cancer therapy, as they can travel through the body and cause cancerous tumors at other sites through metastasis. These cells also may cause resistance ...
Jul 5, 2023
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Matcha, a traditional Japanese tea, has been touted for its health benefits—it can boost mood and mental performance in humans and mice alike—but more mechanistic research is required. Hence, researchers from Japan evaluated ...
Mar 16, 2023
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Fibrotic cancers such as gastric cancers are highly resistant to conventional therapies like immune checkpoint inhibitors. Cancer-associated fibroblasts (CAFs) are an important part of the tumor microenvironment contributing ...
Jan 23, 2023
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Mammals convert the energy stored in adipose (fat) tissue into heat via a process known as thermogenesis. This process is regulated by a family of signaling proteins called sirtuins. A recent study by researchers from Kumamoto ...
Jan 20, 2023
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