La Jolla Institute for Allergy and Immunology

HIV & AIDS

Study establishes benchmarks for HIV vaccine candidates

The development of a vaccine that protects against HIV infections has proven extraordinarily difficult. One of the reasons is that naïve precursor B cells that can give rise to mature B cells producing broadly neutralizing ...

Diseases, Conditions, Syndromes

Dengue immunity can protect against Zika virus

Manifestations of Zika virus (ZIKV) infection differ drastically. Sometimes they are catastrophic, most notably when they cause microcephaly in some babies born to infected mothers. At other times, they are mild and fleeting, ...

HIV & AIDS

Team tests best delivery mode for potential HIV vaccine

For decades, HIV has successfully evaded all efforts to create an effective vaccine but researchers at The Scripps Research Institute (TSRI) and the La Jolla Institute for Allergy and Immunology (LJI) are steadily inching ...

Medical research

The molecular underpinnings of T cell exhaustion

One reason we survive into adulthood is that cell-killing T cells usually recognize and eliminate cancerous or pathogen-infected cells. But prolonged overactivity of immune cells summoned to a tumor or infection site can ...

Diseases, Conditions, Syndromes

T cells join the fight against Zika

The worst of the global Zika virus outbreak may be over but many key questions remain, such as why the virus persists in certain tissues after the systemic infection has cleared; how does the immune system counteract the ...

Diseases, Conditions, Syndromes

Researchers strengthen the case for sexual transmission of Zika virus

Aedes aegypti mosquitoes harboring parasitic Zika virus (ZIKV) are the primary transmitters of virus to humans, potentially causing catastrophic congenital microcephaly in babies born to women bitten by infected mosquitoes. ...

page 2 from 5