La Jolla Institute for Allergy and Immunology

La Jolla Institute for Allergy & Immunology (LIAI) is a non-profit biomedical research institution founded in 1988 and located in La Jolla, California. The Institute's main focus is understanding the immune response to infectious agents and cancers and on advancing progress toward the prevention, treatment, and cure of immune system diseases.

Website
http://www.liai.org/
Wikipedia
http://en.wikipedia.org/wiki/La_Jolla_Institute_for_Allergy_and_Immunology

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Immunology

Researchers find elusive source of most abundant immune cell

Neutrophils—short-lived, highly mobile and versatile—outnumber all other immune cells circulating through the blood stream. Yet, despite the cells' abundance, the progenitor cell that only gives rise to neutrophils had ...

Immunology

Bystander T cells can steal the show in resolving inflammation

In Type 1 diabetes the immune system mistakenly attacks and destroys insulin-producing pancreatic cells, leaving patients dependent on lifelong insulin injections. The putative perpetrators of the attack—which are called ...

Immunology

Western diet depletes artery-protecting immune cells

New research from scientists at the La Jolla Institute For Allergy and Immunology shows how a diet high in fat and cholesterol depletes the ranks of artery-protecting immune cells, turning them into promoters of inflammation, ...

Immunology

Novel genomic tools provide new insight into human immune system

When the body is under attack from pathogens, the immune system marshals a diverse collection of immune cells to work together in a tightly orchestrated process and defend the host against the intruders. For many decades, ...

HIV & AIDS

Study establishes benchmarks for HIV vaccine candidates

The development of a vaccine that protects against HIV infections has proven extraordinarily difficult. One of the reasons is that naïve precursor B cells that can give rise to mature B cells producing broadly neutralizing ...

Diseases, Conditions, Syndromes

Dengue immunity can protect against Zika virus

Manifestations of Zika virus (ZIKV) infection differ drastically. Sometimes they are catastrophic, most notably when they cause microcephaly in some babies born to infected mothers. At other times, they are mild and fleeting, ...

Medical research

The molecular underpinnings of T cell exhaustion

One reason we survive into adulthood is that cell-killing T cells usually recognize and eliminate cancerous or pathogen-infected cells. But prolonged overactivity of immune cells summoned to a tumor or infection site can ...

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