Ludwig Maximilian University of Munich

Medical research

Photopharmacology: Optical control of insulin secretion

Researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich have chemically modified an anti-diabetic agent so as to make its action dependent on light. The resulting prototype compound, termed JB253, induces release of ...

Neuroscience

The rhythm of fear mapped in neuronal networks

Researchers based in Munich and Bordeaux have detected coordinated oscillations in the activities of neuronal networks in two distinct areas of the brain, which are characteristic for a specific fear response.

Cardiology

Atherosclerosis: Induced cell death destabilizes plaques

Many chronic disorders arise from misdirected immune responses. A Ludwig-Maximilians-Universitaet (LMU) team led by Oliver Söhnlein now shows that neutrophils exacerbate atherosclerosis by inducing smooth muscle-cell death ...

Cardiology

The immune response to heart attacks

The damage caused by a heart attack triggers an inflammatory reaction which degrades the affected tissue. This response is orchestrated by immune cells that reside in the nearby pericardial adipose tissue, as a study by an ...

Genetics

Gene therapy for inherited blindness

Retinitis pigmentosa is the most prevalent form of congenital blindness. Using a retinitis pigmentosa mouse model, LMU researchers have now shown that targeted activation of genes of similar function can compensate for the ...

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