Max Planck Institute of Immunobiology and Epigenetics

The Max Planck Institute of Immunobiology and Epigenetics (MPI-IE) in Freiburg is an interdisciplinary research institution that conducts basic research in two key areas of modern biology. Immunobiology is concerned with the ways multicellular organisms defend themselves against pathogens. We study the evolutionary origins and the development of lymphoid organs and immune effector cells, the function of antigen receptors, and the genetic basis of host-pathogen interactions. This information underpins efforts to better diagnose and treat immunodeficiency and inflammatory diseases. Epigenetics is the study of inheritable traits that are not caused by changes in the underlying DNA sequence. Epigenetic mechanisms are crucial for the organization and utilization of our genetic information. Since the susceptibility to diseases can be promoted by epigenetic dysfunction, epigenetic research has far-reaching implications for diagnosis and therapy of human disease.

Address
Stuebeweg 51 79108 Freiburg Germany
Website
https://www.ie-freiburg.mpg.de/

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Immunology

Innate lymphoid cells regenerate within lung

The immune system is equipped with numerous cell types that effectively fight the various pathogens, humans can encounter during their lives. T cells, for example, have a receptor through which they can specifically recognize ...

Genetics

Immune functions traded in for reproductive success

Deep-sea anglerfishes employ an incredible reproductive strategy. Tiny dwarfed males become permanently attached to relatively gigantic females, fuse their tissues and then establish a common blood circulation. In this way, ...

Medical research

Brothers in arms: The brain and its blood vessels

The brain is our most energy-hungry and metabolically active organ. It is responsible for our thoughts, ideas, movement and ability to learn. Our brain is powered by 600 km of blood vessels that bring it nutrients and remove ...