Sanford Burnham Prebys Medical Discovery Institute

Sanford Burnham Prebys Medical Discovery Institute (SBP) is an non-profit medical research institute with locations in La Jolla, California and Orlando, Florida. There are more than 850 scientists at SBP blending cutting-edge fundamental research with robust drug discovery to address unmet clinical needs in the areas of cancer, neuroscience, immunity, and metabolic disorders.

Website
http://www.sbpdiscovery.org/
Wikipedia
https://en.wikipedia.org/wiki/Sanford_Burnham_Prebys_Medical_Discovery_Institute

Some content from Wikipedia, licensed under CC BY-SA

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Neuroscience

ALS research reveals new treatment approach

On June 2, 1941, at the age of 37, baseball player Lou Gehrig succumbed to amyotrophic lateral sclerosis (ALS), a progressive muscle degeneration disease. Today, nearly 80 years following his death, scientists are still searching ...

Oncology & Cancer

Conquering cancer's infamous KRAS mutation

KRAS is one of the most challenging targets in cancer. Despite its discovery more than 60 years, researchers still struggle to inhibit its mutated form—earning its reputation as "undruggable." Yet, the hunt for an Achilles' ...

Oncology & Cancer

Gut microbiome directs the immune system to fight cancer

The advent of immune checkpoint inhibitors—which "release the brakes" of the body's immune system to launch an efficient tumor attack—are a major breakthrough in cancer immunotherapy. However, these treatments don't work ...

Oncology & Cancer

Helping infants survive brain cancer

Choroid plexus carcinoma (CPC) is a particularly challenging type of brain cancer. The tumor most commonly arises in infants under the age of one—who are too young to undergo radiation treatment. Only 40 percent of children ...

Oncology & Cancer

How prostate cancer becomes treatment resistant

The development of effective anti-androgen therapies for prostate cancer is a major scientific advance. However, some men who receive these targeted treatments are more likely to develop a deadly treatment-resistant prostate ...

Oncology & Cancer

Targeted treatment shrinks deadly pediatric brain tumors

Chemotherapy and radiation are effective cancer treatments because they kill rapidly dividing cells, including tumor cells. But for children—whose tiny bodies are still growing—these treatments can cause lifelong damage. ...

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