Sanford Burnham Prebys Medical Discovery Institute

Genetics

COVID-19: Scientists identify human genes that fight infection

Scientists at Sanford Burnham Prebys have identified a set of human genes that fight SARS-CoV-2 infection, the virus that causes COVID-19. Knowing which genes help control viral infection can greatly assist researchers' understanding ...

Oncology & Cancer

Starving tumors by blocking glutamine uptake

Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a drug candidate that blocks the uptake of glutamine, a key food source for many tumors, and slows the growth of melanoma. The drug is a small ...

Medications

Leprosy drug holds promise as at-home treatment for COVID-19

A Nature study authored by scientists at Sanford Burnham Prebys Medical Discovery Institute and the University of Hong Kong shows that the leprosy drug clofazimine, which is FDA approved and on the World Health Organization's ...

Medical research

New drug combination shows promise as powerful treatment for AML

Scientists have identified two drugs that are potent against acute myeloid leukemia (AML) when combined, but only weakly effective when used alone. The researchers were able to significantly enhance cancer cell death by jointly ...

Diseases, Conditions, Syndromes

Scientists identify 'immune cop' that detects SARS-CoV-2

Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified the sensor in human lungs that detects SARS-CoV-2 and signals that it's time to mount an antiviral response. The study, published today in Cell ...

Oncology & Cancer

Research reveals why some tumors have different makeup of cells

Molecular changes in cells called fibroblasts, which help provide support for tissues throughout the body, may explain why one type of colon cancer doesn't respond to therapy, according to a team of researchers from Weill ...

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