In a paper published in Nature Immunology, scientists from Seattle Children's Research Institute reveal how a rare group of white blood cells called basophils play an important role in the immune response to a bacterial infection, ...
Jan 21, 2019
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New research from Seattle Children's Research Institute and UW Medicine's Sports Health and Safety Institute found concussion rates among football players ages 5-14 were higher than previously reported, with five out of every ...
Dec 13, 2018
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Seattle Children's has opened a chimeric antigen receptor (CAR) T-cell immunotherapy trial for children and young adults with relapsed or refractory non-central nervous system EGFR-expressing solid tumors. In the phase 1 ...
Aug 7, 2018
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Seattle Children's has opened a pioneering chimeric antigen receptor (CAR) T-cell immunotherapy trial for children and young adults with relapsed or refractory HER2-positive central nervous system (CNS) tumors where CAR T ...
Jun 19, 2018
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Advances in engineering T cells to treat cancer are paving the way for new immunotherapies targeted at autoimmune diseases, including type 1 diabetes. Now, researchers are also investigating therapies that reprogram T cells ...
Dec 13, 2017
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Results from a phase 2 clinical trial, presented by Seattle Children's Research Institute at the 59th American Society of Hematology (ASH) Annual Meeting, show that the drug Abatacept (Orencia) nearly eliminated life-threatening ...
Dec 9, 2017
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After seeing promising results in phase 1 of the Pediatric Leukemia Adoptive Therapy (PLAT-02) trial with 93 percent of patients with relapsed or refractory acute lymphoblastic leukemia (ALL) achieving complete initial remission, ...
Jul 27, 2017
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In an effort to find new strategies to personalize treatment for pediatric patients, Seattle Children's has opened the first clinical trial applying next-generation T-cell receptor (TCR) sequencing and single-cell gene expression ...
May 23, 2017
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A study published today in The Journal of Pediatrics suggests that early-onset pancreatitis in children is strongly associated with certain genetic mutations and family history of pancreatitis.
May 10, 2017
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After phase 1 results of Seattle Children's Pediatric Leukemia Adoptive Therapy (PLAT-02) trial have shown T-cell immunotherapy to be effective in getting 93 percent of patients with relapsed or refractory acute lymphoblastic ...
May 9, 2017
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