Established in 1975, University of North Carolina Lineberger Comprehensive Cancer Center is in the top tier of nationally- recognized comprehensive cancer centers, one of only 47 designated by the National Cancer Institute. We are the only public comprehensive cancer center serving the state and people of North Carolina. With research that spans the spectrum from the laboratory to the bedside to the community, UNC Lineberger members work to understand the causes of cancer at the genetic and environmental levels, to conduct groundbreaking laboratory research, and to translate findings into pioneering and innovative clinical trials.
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Researchers at the UNC Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center have found that mailing human papillomavirus (HPV) self-collection tests and offering assistance to book in-clinic ...
May 11, 2023
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A multi-institutional national study has identified unique molecular features responsible for the development and progression of metastatic breast cancer. One of the key features involves changes in the immune system that ...
Jan 9, 2023
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Researchers at UNC Lineberger Comprehensive Cancer Center and colleagues have found that measuring activation of immune-system B cells may be better than measuring either T-cell activation or the total number of immune cells ...
Jan 5, 2023
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Researchers at UNC Lineberger Comprehensive Cancer Center have found a possible way to overcome barriers that block effective anti-cancer immune responses, thereby opening the potential for more effective immunotherapies ...
Oct 5, 2022
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People with advanced cancer who communicated their symptoms weekly using an electronic survey had about a one-third better physical function and over a 15% better control of their symptoms compared to those who were evaluated ...
Jun 6, 2022
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Researchers at the University of North Carolina at Chapel Hill and the UNC Lineberger Comprehensive Cancer Center have uncovered a new role of a chromatin-modulatory enzyme, termed EZH2, during cancer development. They then ...
Feb 24, 2022
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UNC Lineberger Comprehensive Cancer Center researchers have demonstrated that a novel combination of two drugs that act as targeted inhibitors, delivered in a nanoparticle formulation, extend the survival of mice with medulloblastoma. ...
Jan 26, 2022
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Researchers at UNC Lineberger Comprehensive Cancer Center have taken a major step forward in melding two key methods for studying breast cancer: one by genetic analysis and the second by looking at the architecture of cells, ...
Dec 8, 2021
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Pairing a newly developed gel with immunotherapy that was delivered to post-surgical mouse brains with glioblastoma, a highly malignant and deadly cancer, improved the immunotherapy's effectiveness, report researchers from ...
Oct 6, 2021
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Researchers at the University of North Carolina at Chapel Hill and the UNC Lineberger Comprehensive Cancer Center have uncovered a new mechanism that activates specific genes, leading to the development of cancers.
Jun 23, 2021
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