University of Bonn

Oncology & Cancer

Ceritinib offers a promising target for cancer immunotherapy

Many tumor cells mist themselves with a protective perfume that disables the immune system. But a drug already approved for other purposes can apparently render this weapon harmless. This is shown in a study by the University ...

Cardiology

Mechanism discovered that leads to ANCA-associated vasculitis

The immune system can become the enemy when mechanisms that are actually protective get out of control. In ANCA-associated vasculitis, excessive inflammatory reactions lead to pulmonary hemorrhages that can be fatal if left ...

Neuroscience

Timing of neuron development determines what they can become

When it comes to royalty, things are clear: The monarch's first child inherits the crown. Siblings born later must make do with a less glamorous profession. This is quite similar for some nerve cells in the brain. In their ...

Diseases, Conditions, Syndromes

COVID-19: New energy for flagging immune cells

In severe COVID-19 patients, metabolism produces insufficient amounts of certain energy-rich compounds called ketone bodies. However, these energy carriers are needed by two important cell types in the immune system in order ...

Overweight & Obesity

Molecule boosts fat burning

Normally, fat cells store energy. In brown fat cells, however, energy is dissipated as heat—brown fat thus serves as a biological heater. Most mammals therefore have this mechanism. In humans it keeps newborns warm; in ...

Medical research

'Growing end' of inflammation discovered

Redness, swelling and pain are signs of inflammation. It serves to protect the body from pathogens and foreign substances. Researchers from the Universities of Bonn and Cologne were able to show that inflammatory reactions ...

Neuroscience

Enzyme prevents brain activity from getting out of control

Our bodies have the ability to modify the contacts between neurons. Among other things, this is how it prevents brain activity from getting out of control. Researchers from the University Hospital Bonn, together with a team ...

Immunology

A new approach against chronic inflammation

The cells in our body have a sophisticated alarm system, the inflammasome. Its central component is the so-called ASC protein. In the event of danger, such as an attack by a pathogen, many of these molecules join together ...

Pediatrics

Protein boosts height growth in girls

Quite a few young men would like to increase their height. However, a study by nutritionists at the University of Bonn shows that they do not benefit from increased protein intake in terms of their adult height. In contrast, ...

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