University of Bonn

Immunology

New intracellular 'smoke detector' discovered

Researchers at the Universities of Bonn and Singapore have discovered a new intracellular "smoke detector." The sensor warns of damage to the mitochondria—the microscopic power plants that supply the cell with energy. If ...

Immunology

Study shows immune cells have a backup mechanism

The enzyme TBK1 is an important component of the innate immune system that plays a critical role in the defense against viruses. Upon mutation-induced loss of TBK1 function, patients show an increased susceptibility to viral ...

Medical research

Tracking down leaks in the blood-brain barrier

In epilepsy research, it has long been assumed that a leaky blood-brain barrier is a cause of inflammation in the brain. Using a novel method, researchers from Bonn University Hospital (UKB) and the University of Bonn have ...

Diseases, Conditions, Syndromes

New compound inhibits influenza virus replication

Viruses use the molecular repertoire of the host cell to replicate. Researchers from the Cluster of Excellence ImmunoSensation2 at the University of Bonn, together with Japanese researchers, want to exploit this for the treatment ...

Gastroenterology

AI improves colorectal cancer screening in Lynch syndrome

People with Lynch syndrome have a higher hereditary risk of colon cancer. Despite regular endoscopic surveillance, it remains elevated in those affected. Researchers at the National Center for Hereditary Tumor Diseases (NZET) ...

Genetics

How nerve and vascular cells coordinate their growth

Nerve cells need a lot of energy and oxygen. They receive both through the blood. This is why nerve tissue is usually crisscrossed by a large number of blood vessels. But what prevents neurons and vascular cells from getting ...

Diseases, Conditions, Syndromes

New findings on memory impairment in epilepsy

People with chronic epilepsy often experience impaired memory. Researchers at the University of Bonn have now found a mechanism in mice that could explain these deficits. The German Center for Neurodegenerative Diseases (DZNE) ...

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