Uppsala University

Medical research

Gut epithelium muscles up against infection

To maximize absorption of nutrients from the diet, the intestinal mucous membrane has a large surface area. However, this also makes it vulnerable to attack from aggressive gut microbes. A new study by Uppsala University ...

Genetics

Mutations in the neurochondrin gene linked to epilepsy

Mutations in the neurochondrin (NCDN) gene can cause epilepsy, neurodevelopmental delay and intellectual disability. The gene mutation significantly impairs contacts and signaling between neurons in the brain. This is the ...

Diseases, Conditions, Syndromes

Innate immune system worsens the situation in severe COVID-19

In patients with severe COVID-19, the innate immune system overreacts. This overreaction may underlie the formation of blood clots (thrombi) and deterioration in oxygen saturation that affect the patients. This is shown in ...

Medications

Beta blockers can repair malformed blood vessels in the brain

Propranolol, a drug that is efficacious against infantile haemangiomas ("strawberry naevi," resembling birthmarks), can also be used to treat cerebral cavernous malformations, a condition characterized by misshapen blood ...

Medical research

Metabolic response behind reduced cancer cell growth

Researchers from Uppsala University show in a new study that inhibition of the protein EZH2 can reduce the growth of cancer cells in the blood cancer multiple myeloma. The reduction is caused by changes in the cancer cells' ...

Diseases, Conditions, Syndromes

New clues to how SARS-CoV-2 infects cells

The molecular details of how SARS-CoV-2 enters cells and infects them are still not clear. Researchers at Uppsala University have tested the bioinformatic predictions made by another research group and have identified receptors ...

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