Washington University School of Medicine in St. Louis

Medical research

Newfound autoimmune syndrome causes muscle pain, weakness

A previously unknown autoimmune muscle disease involving sudden onset of debilitating muscle pain and weakness has been identified by researchers at Washington University School of Medicine in St. Louis. The syndrome easily ...

Medical research

Lithium boosts muscle strength in mice with rare muscular dystrophy

Standing up from a chair, climbing stairs, brushing one's hair – all can be a struggle for people with a rare form of muscular dystrophy that causes progressive weakness in the shoulders and hips. Over time, many such people ...

Oncology & Cancer

'Jumping genes' drive many cancers

Mistakes in DNA are known to drive cancer growth. But a new study, from Washington University School of Medicine in St. Louis, heavily implicates a genetic phenomenon commonly known as "jumping genes" in the growth of tumors.

Genetics

Gene therapy blocks peripheral nerve damage in mice

Nerve axons serve as the wiring of the nervous system, sending electrical signals that control movement and sense of touch. When axons are damaged, whether by injury or as a side effect of certain drugs, a program is triggered ...

Oncology & Cancer

Obesity linked to increased risk of early-onset colorectal cancer

Women who are overweight or obese have up to twice the risk of developing colorectal cancer before age 50 as women who have what is considered a normal body mass index (BMI), according to new research led by Washington University ...

Oncology & Cancer

Scientists identify weak point in deadly eye melanoma

A natural plant compound exploits a newly identified Achilles' heel in a cancer of the eye, uveal melanoma. In human cancer cells growing in the lab, the compound shuts down the overactive signaling that drives uveal melanoma ...

Neuroscience

CRISPR technology targets mood-boosting receptors in brain

An estimated 13 percent of Americans take antidepressant drugs for depression, anxiety, chronic pain or sleep problems. For the 14 million Americans who have clinical depression, roughly one third don't find relief with antidepressants.

Psychology & Psychiatry

Perfectionism in young children may indicate OCD risk

Studying young children, researchers at Washington University School of Medicine in St. Louis found that kids who possess tendencies toward perfectionism and excessive self-control are twice as likely as other children to ...

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