Page 2 - Whitehead Institute for Biomedical Research

Oncology & Cancer

Drug-resistant cancer cells create own Achilles heel

The cells of most patients' cancers are resistant to a class of drugs, called proteasome inhibitors, that should kill them. When studied in the lab, these drugs are highly effective, yet hundreds of clinical trials testing ...

Oncology & Cancer

Scientists identify a surprising new source of cancer stem cells

Whitehead Institute researchers have discovered that a differentiated cell type found in breast tissue can spontaneously convert to a stem-cell-like state, the first time such behavior has been observed in mammalian cells. ...

Medical research

Type 1 diabetes from a beta cell's perspective

Type 1 diabetes is an autoimmune disease that occurs when T-cells in the immune system attack the body's own insulin-producing cells, called beta cells, in the pancreas. Usually diagnosed in children and young adults, type ...

Medical research

Rett syndrome gene dysfunction redefined

Whitehead Institute researchers have redefined the function of a gene whose mutation causes Rett syndrome, a neurodevelopmental autism spectrum disorder. This new research offers an improved understanding of the defects found ...

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