%PDF-1.7 % 16 0 obj << /Type /Page /Parent 1 0 R /LastModified (D:20181117122217-05'00') /Resources 2 0 R /MediaBox [0.000000 0.000000 595.276000 841.890000] /CropBox [0.000000 0.000000 595.276000 841.890000] /BleedBox [0.000000 0.000000 595.276000 841.890000] /TrimBox [0.000000 0.000000 595.276000 841.890000] /ArtBox [0.000000 0.000000 595.276000 841.890000] /Contents 17 0 R /Rotate 0 /Group << /Type /Group /S /Transparency /CS /DeviceRGB >> /Annots [ 6 0 R 8 0 R 9 0 R ] /PZ 1 >> endobj 17 0 obj <> stream x\rF}Wte*@e{}Vm*zvυ)啓2)Hgzϙ3t\C?o˯:{zO^DAhj : ;FBx_ͳ4I͡lΞJ<'g@\iۋfI~;<%o\AF?sob?|4YQ)4gy]mQ˔u3LyRf6\qր\)5giX3H4LJ/3yYjщ-'D}i*P 6C$2,ZQ:%Kh 3,l֥h1TtĕRUzhm=~i9Er!vmy+{ B4orkXەh9W8 41m2:j)κix0 '/lD)6 :9~|Ynё Nu0`#)^㇘ZCBqRlc>5s:?$4IޥGpY47q"FzWcD9~pq>DŽ"[Y]/T;*䵰QP VZ)G1), 晅ذ={RLXH\v5$Qi٥S:BorX~~p!eRo$5 䎹T5 Z; u-;X y%+FQh *#L(NX VҭX6{VF4_%32B90b[;bXGV"\?7ρZd5Fr%t(a*hx%bM2/ ` (٫.?< sk:Gp[Qx%imޖ2}+aq)0K9D8k"km+Q3)[qcYcqZ\æ_Bjz% =R{Dmȍ甫tlj'[݆Ԯj W_+6ߐ_WWF3M ++sM:TrM< gz`Wj>/lLfvhvKc CY \,]h&K;+n7B<7\_yCh{ Z9ËRr1PP}>[c7L>TjLOb_$NcnyeZ,!f}f='KȚ_;Qj*s6 &xqbqo%VgB*fv(x/Qfi/\9{bq+*'(!=QoG%ȑ ОS_@[j5lQf%;Ӄͼs7ՒZ׋~GZr2cXya^k LbwkiߩgVmr1}0Bd 74$iX>ӟ>Ӵ<fmCTdy_F ^6?q}EE)`[*ҚoȴW@nLwEGY{wy댤5QT!{ VNlB AD-c?kvǾ94L]nF8y8|p%qh$ԤO6h \ v2'/b+V(_RtRQD+EEj.!`)[Z!* `Ңkz7^y[Ӯ)JNo2F [vx,(&Fa${AˊZ0O<&[gXk =fm%P.u'6=! jS [HM,5st@&>Rl6t:P9$-VXRx iyb",1Ps$]#gLm1xb#;> #-xUZޥu86Vɻ -z5b9%#<|x47Zgs֜=->񧩺;aA- (]̱6L"C[PlҵeW=2]?F 9D cRpT_1غ\ޭcn iLͥA=6(X̒7X80SAYycim~О- wƪugO%vtqG'ZѺy;)>:%;.Y柃55ےSRG|s~I)LlP9=9ӷs#sJ w 7NMu@orԂ-j$ %xϻ z?S{hb}E%3:`ALjY߰{Z&QvvIݪ(BTح+9]~oy37qXp:h,(7&Pd^ (': rAHe!5ѡqgz| lz( b\dLo>:u(AWjT x 7:tʈ`8ܒr`q̭lIPЉPEh0>Ci.Gƙ'm =Yެbz[46%JGK[ÒR%8:wx=}bͲl"'HQ1l /[xs0Ib>Q¢H_> /Annots [ 10 0 R 11 0 R 12 0 R 13 0 R 14 0 R 15 0 R ] /PZ 1 >> endobj 19 0 obj <> stream x[r}+ve*[ѭu050CyhKmARV_r~v20EEezw}>~` >௿O %a X_0_tpA_B=H- 6<Sx/jK) 9qz.>+&5m{/6O>A>~"yꄈ5nS`lsm`VV;dhHdTLդ0% I5VN &E(4t \=V%M`֏?܈w" mkCC1@   Qfjd"b%G7HG-6TPu Mե.D!QZvczގ81ӥDX0qZMcB.G/ujG1U_a{SƊ3M*B٫E ݒϕ6F h{*B??4KVv+N/\jyAwXIE994?:~|e GaC0" 8z b!kӭ宱m8wޔgLrGcMa%iǣۜO 3ǺVx۲B+ѓOHr/Ӎ'+6D&GB/z;7 /j_ޔ旵!fxht׬Ry܋rƒtw%z$$=/wp 6ׅw3)(rUo$oz-h/}Azi})ȯy8i,H2 OX0ץdO]˕X!󊖬B:Kr[]nwmĔ''P5?6ՍsJQ::׻i:%n/DIl5I_?k3$)LI;D7be5rC"KҡSKZK/Z^!ㆭcmiNsvsSпTn%;5;M>0u@ _Ǖqs8oMlFDow:Rib? eFeHN 3l0 q %f԰ eSK+JMJ`-Rы"57{F.w:kyCb@ߙ%OnӷnyYDl90OޣgٯOcz]מ*r xx;rw;٥X&8\th~=᾽؞}LRKI_W4w{]$t^9Ix'c^Lw endstream endobj 1 0 obj << /Type /Pages /Kids [ 16 0 R 18 0 R ] /Count 2 >> endobj 3 0 obj <> endobj 5 0 obj <> endobj 7 0 obj <> endobj 20 0 obj <> stream JFIFHHExifMM* z(1>?QQ Q HHPaint.NET v3.5.10z%u0`:oCC." }!1AQa"q2#BR$3br %&'()*456789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz w!1AQaq"2B #3Rbr $4%&'()*56789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz ?(f 1T$`9Sw(B@;~(]Cd꾫Es:aݻd2\(2F][&]ۢϲ|W͵L@A A 8 (CĝCglZE/ |Ezє{ xQʒ@[ྊ\/I4R0?6.7`ŴwPu|3/Z@Ogi}cFdFKoj?~8|p_A<ĺOkGPK $wRmkmF;YVx&rLj#p ׭axf|s$Ӿc:Qwm]N)Cψ[eYba98xB+oTÚwcRþ$U[ ?qΙ{&jv6Xo$=ԗ&7zgAxIִ.$3,mwc{+%g[!U@&Fϻm/#hci'7n[%It.&/ֶ+Zl~:wi~D>$}o+}@.[/+B6mnt8bi{zc.~F{eUe86g3 VT&> BK VؘXzSMesoM_&ϔIÍK?+hڿnt_ K]H '̽yrWA=O+|"!gɤItXe>Xs hwwG Eouqa /ş_~~'x} ]_^]/ 蚼:<cu/ h&omEۯicǪ\[,k}_uS}㏆W]G^tmf`Ks ]=va&h9n忔>75NWQτ0of,E (˰8hBC_ Jq'W UQKz,N>+`S%}b5ISJ]+(&QVN>eoy7xG4[]]3K{i$I>g-(mbynLIC,"*3f?-%`lfPx涽X"H'h"ֈ(TfeU:܉,a,R*I4xcxalOhGр|ia$cg,{gAHEu->]F,{-.,EX"I$XQD/3R.{{T&ҭ%4[OPnx"HhM :e}-Լ'=s:\iZ<+Lj5+1AɮLZx-☽G3 1I"kuχ+A}5'NxI8 gJk[oenm!x,=n=>}kjPx~M񧍼5k45a,RLiȖTFQMR&K;}r+XkY[y>2F=2~6>Gmi++<[WF76MH4>;;Kf۽ъM3ZE}c㿈*- -.|G5uI![ YR$$A>Eyׇ|7u;n>4׭JϷR[h!rVr\{~Ϛ >0jMg?_y_ Do/x;ÚƏi a𶕦f|Eqgk4V^RY]}F,/J%ՌAud%:x3Hg_4[+^ ҴKaXF'n.]Z(i$bef5GO:u]/a~.3N4xiG*a8ާ-U){G nJEڿ[m7wv5MYp|'gm # #%B?|鿲w­{+_|Q#VkxcZޛ{I]Wyak}..i˨iY9QwOA~hf{+ |Y;cڴ27G>|H,na8o; CEO,ZLP?SHK} e92W7/1aj¤aڄq4 қS7,5]%EƔc/uҒw\r/EnT y>!V+VK4X^Y{;+Ӫ=MqslEn?Zz'Ë}^2xĺGf70/M~*DU=坍G{wwvci%vZ$GY&J9dkՀ\6hs.F*ĩ"+S%s*{ qqDj3$ q^T24,Cn +=j񟍼q5k'\%ݎ{ͦuyq4X$y<ك2Ey%™|Icw]3#R[`{KցY [1*kLOdw ^OAkЏb<¿ <=6x0ׄ>(=*[ t]9-?IZ@}/>FۃQ@ endstream endobj 4 0 obj << /Type /XObject /Subtype /Form /FormType 1 /Filter /FlateDecode /BBox [0.000000 0.000000 595.276000 76.535433] /Matrix [1 0 0 1 0 0] /Resources << /ProcSet [/PDF /Text /ImageB /ImageC /ImageI] /Font << /F2 5 0 R /F1 3 0 R >> /XObject << /I0 20 0 R >> >> /Length 197 >> stream xKkBA WeI&ڊU/ nʥBf8A3!(X4`JQj*Aj͕197f hkL[=µrw]F D%x2WC0 9)Z ^Wh}29yyu?4g=bT1߻a endstream endobj 2 0 obj << /ProcSet [/PDF /Text /ImageB /ImageC /ImageI] /Font << /F1 3 0 R /F2 5 0 R /F3 7 0 R >> /XObject << /XT4 4 0 R /I0 20 0 R >> >> endobj 6 0 obj <> /H /I>> endobj 8 0 obj <> /H /I>> endobj 9 0 obj <> /H /I>> endobj 10 0 obj <> /H /I>> endobj 11 0 obj <> /H /I>> endobj 12 0 obj <> /H /I>> endobj 13 0 obj <> /H /I>> endobj 14 0 obj <> /H /I>> endobj 15 0 obj <> /H /I>> endobj 21 0 obj << /Title (One-dose gene therapy produces clotting factor, safely stops bleeding in hemophilia B patients) /Subject (One-dose gene therapy produces clotting factor, safely stops bleeding in hemophilia B patients) /Creator (Science X Network) /Producer (TCPDF 6.2.25 \(http://www.tcpdf.org\)) /CreationDate (D:20181117122217-05'00') /ModDate (D:20181117122217-05'00') /Trapped /False >> endobj 22 0 obj << /Type /Metadata /Subtype /XML /Length 4429 >> stream application/pdf One-dose gene therapy produces clotting factor, safely stops bleeding in hemophilia B patients One-dose gene therapy produces clotting factor, safely stops bleeding in hemophilia B patients 2018-11-17T12:22:17-05:00 Science X Network 2018-11-17T12:22:17-05:00 2018-11-17T12:22:17-05:00 TCPDF 6.2.25 (http://www.tcpdf.org) uuid:ac62ae21-6c85-3519-2b66-1d18326c6287 uuid:ac62ae21-6c85-3519-2b66-1d18326c6287 http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text endstream endobj 23 0 obj << /Type /Catalog /Version /1.7 /Pages 1 0 R /Names << >> /ViewerPreferences << /Direction /L2R >> /PageLayout /SinglePage /PageMode /UseNone /OpenAction [16 0 R /FitH null] /Metadata 22 0 R >> endobj xref 0 24 0000000000 65535 f 0000006299 00000 n 0000012834 00000 n 0000006366 00000 n 0000012333 00000 n 0000006472 00000 n 0000012980 00000 n 0000006583 00000 n 0000013223 00000 n 0000013471 00000 n 0000013717 00000 n 0000013962 00000 n 0000014209 00000 n 0000014453 00000 n 0000014696 00000 n 0000014981 00000 n 0000000015 00000 n 0000000497 00000 n 0000003507 00000 n 0000004013 00000 n 0000006697 00000 n 0000015199 00000 n 0000015849 00000 n 0000020361 00000 n trailer << /Size 24 /Root 23 0 R /Info 21 0 R /ID [ ] >> startxref 20571 %%EOF